About this Research Topic
Alarmingly, with the ever-increasing of antimicrobial resistance over the last five decades, it remains one the major public health concerns. To counteract the expansion of drug resistance problem, innovative but green measures could be utilized. In this regard, ionic liquids (ILs) and deep eutectic solvents (DESs) have been exploited in various biological applications, thanks to their good antimicrobial and anticancer activities. Owning to their intriguing characteristics including, thermal and chemical stability, ILs and DESs have been implanted in a multitude of pharmaceutical applications. More importantly, huge attention has been focusing on exploiting their green and sustainable nature.
Reporting their antimicrobial effects, researchers have highlighted the role of ILs and DESs against skin related infections, biofilms and multi-drug resistant bacterial infections. Moreover, recent findings elucidated some of the underlying antimicrobial mechanisms. On the other hand, many of the existing antimicrobial drugs were formulated into novel ionic liquids or eutectic mixtures to enhance their antimicrobial activities.
The tunability of ILs and DESs could be exploited widely to tackle microbial resistance, such as focusing on potential synergistic effects, modulating their mechanism of actions and enhancing the drug delivery of existing drugs.
The main aim of this research topic is to exploit the advanced biological applications of DESs against infectious diseases, mainly the ones caused by resistance pathogens.
Focusing on their natural origin, DESs could be widely implemented against a multitude of infections, hence, this topic will spotlight more advanced antimicrobial applications of DESs. On one hand, exploring a greener tactic in this area of microbial resistance represent a main objective of this topic. On the other hand, this topic would highlight the wide applications of DESs in pharmaceutical microbiology field. Lastly, we aim to demonstrate the advantages of enhancing the antimicrobial activity of existing drugs through different approach based on DESs of the existing drugs.
New research topics covering the new antimicrobial drugs based on DESs and DESs related approaches tackling microbial resistance issues would be within the scope of this research topic. The contributors are expected to cover the following topics with Original Research articles, Reviews, and Mini-Reviews:
• Exploring green tactics based on DESs to tackle the infectious diseases
• Exploring approaches to enhance the biological activities of DESs in the microbiology field
• Highlighting novel mechanisms related to the antimicrobial activities of DESs
• Addressing the pharmaceutical limitation of some drugs and thus enhancing their antimicrobial activity
• Evaluating the possibility of forming synergistic combinations between antibiotics and DES
Reporting their antimicrobial effects, researchers have highlighted the role of ILs and DESs against skin related infections, biofilms and multi-drug resistant bacterial infections. Moreover, recent findings elucidated some of the underlying antimicrobial mechanisms. On the other hand, many of the existing antimicrobial drugs were formulated into novel ionic liquids or eutectic mixtures to enhance their antimicrobial activities.
The tunability of ILs and DESs could be exploited widely to tackle microbial resistance, such as focusing on potential synergistic effects, modulating their mechanism of actions and enhancing the drug delivery of existing drugs.
The main aim of this research topic is to exploit the advanced biological applications of DESs against infectious diseases, mainly the ones caused by resistance pathogens.
Focusing on their natural origin, DESs could be widely implemented against a multitude of infections, hence, this topic will spotlight more advanced antimicrobial applications of DESs. On one hand, exploring a greener tactic in this area of microbial resistance represent a main objective of this topic. On the other hand, this topic would highlight the wide applications of DESs in pharmaceutical microbiology field. Lastly, we aim to demonstrate the advantages of enhancing the antimicrobial activity of existing drugs through different approach based on DESs of the existing drugs.
New research topics covering the new antimicrobial drugs based on DESs and DESs related approaches tackling microbial resistance issues would be within the scope of this research topic. The contributors are expected to cover the following topics with Original Research articles, Reviews, and Mini-Reviews:
• Exploring green tactics based on DESs to tackle the infectious diseases
• Exploring approaches to enhance the biological activities of DESs in the microbiology field
• Highlighting novel mechanisms related to the antimicrobial activities of DESs
• Addressing the pharmaceutical limitation of some drugs and thus enhancing their antimicrobial activity
• Evaluating the possibility of forming synergistic combinations between antibiotics and DES
Keywords: Ionic Liquids, Deep eutectic solvents, antimicrobial resistance, Therapeutic deep eutectic solvents
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
