About this Research Topic
Cardiovascular diseases are the leading cause of death globally. Only in the USA, about 805,000 people have a heart attack every year, or 1 person every 40 seconds. Despite recent advances, multiple aspects still need to be addressed for a complete understanding of these diseases and their prevention and treatments.
The autonomic nervous system (ANS) unconsciously regulates several aspects of the cardiovascular system, such as cardiac muscle contraction, heart rate, and blood pressure. It is part of the peripheral nervous system and in turn, is formed by two cooperative and balanced systems: the sympathetic (SNS) and parasympathetic nervous systems (PNS). While the "fight or flight" reaction, such as increase in heart-rate, is regulated by the SNS, the "rest and digest" response is controlled by the PNS. After an acute or chronic myocardial infarction, autonomic regulation function becomes abnormal, with increased sympathetic and reduced parasympathetic activity, triggering further decline and heart failure.
Frontiers in Neuroscience is looking to address key aspects of myocardial infarction from an autonomic neuroscience perspective in order to promote important discussions around this topic and to facilitate knowledge dissemination. We welcome submission of Original Research, Review, Methods, and Perspective articles. Sub-themes for this Research Topic may include, but are not limited to:
• Neuromodulation of the autonomic nervous system as prevention and treatment
• Vagal nerve stimulation for autonomic regulation
• Sympathetic and parasympathetic nervous system imbalances and their role in myocardial infarction
• Autonomic regulation of cardiovascular function
• Biomarkers of autonomic function and dysfunction
The autonomic nervous system (ANS) unconsciously regulates several aspects of the cardiovascular system, such as cardiac muscle contraction, heart rate, and blood pressure. It is part of the peripheral nervous system and in turn, is formed by two cooperative and balanced systems: the sympathetic (SNS) and parasympathetic nervous systems (PNS). While the "fight or flight" reaction, such as increase in heart-rate, is regulated by the SNS, the "rest and digest" response is controlled by the PNS. After an acute or chronic myocardial infarction, autonomic regulation function becomes abnormal, with increased sympathetic and reduced parasympathetic activity, triggering further decline and heart failure.
Frontiers in Neuroscience is looking to address key aspects of myocardial infarction from an autonomic neuroscience perspective in order to promote important discussions around this topic and to facilitate knowledge dissemination. We welcome submission of Original Research, Review, Methods, and Perspective articles. Sub-themes for this Research Topic may include, but are not limited to:
• Neuromodulation of the autonomic nervous system as prevention and treatment
• Vagal nerve stimulation for autonomic regulation
• Sympathetic and parasympathetic nervous system imbalances and their role in myocardial infarction
• Autonomic regulation of cardiovascular function
• Biomarkers of autonomic function and dysfunction
Keywords: Myocardial Infarction, Autonomic nervous system, Sympathetic nervous system, Parasympathetic nervous system
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
