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About this Research Topic

Manuscript Submission Deadline 26 October 2023
Manuscript Extension Submission Deadline 26 November 2023

Pigmented lesions of the oral cavity constitute an important diagnostic challenge for pathologists as they can be the result of different etiopathogenic mechanisms such as benign paraphysiological changes, systemic diseases or malignant lesions. Differential diagnosis is particularly important and useful as it allows for the discrimination, with good safety, between typical or atypical pigmented lesions from exogenous pigmentations or lesions of other nature.

However, there remains a portion of oral mucosal nevi that can be particularly insidious and misdiagnostic with the dreaded oral malignant melanoma (OMM).

For oral pigmented lesions and pigmented lesions at other parts of the body, the anatomo-pathological diagnosis consists of a morphological aspect (Hematoxylin-Eosin, H&E), an assessment using ancillary techniques of immunohistochemistry (IHC), and a increasingly active part of molecular biology. In this Research Topic, we aim to address this issue with contributions that shed light on these important aspects of oral pathology.

In this Research Topic, authors are invited to submit case reports, data reports, perspectives, general commentary, original articles and reviews relating to the pathological diagnosis of oral pigmented lesions at the dawn of 2023. Contributions relating to the field of molecular diagnostics applied to oral mucosa nevi/OMM are also welcome.

Keywords: Oral pathology, pigmented lesions, nevi, malignant melanoma, differential diagnosis


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Pigmented lesions of the oral cavity constitute an important diagnostic challenge for pathologists as they can be the result of different etiopathogenic mechanisms such as benign paraphysiological changes, systemic diseases or malignant lesions. Differential diagnosis is particularly important and useful as it allows for the discrimination, with good safety, between typical or atypical pigmented lesions from exogenous pigmentations or lesions of other nature.

However, there remains a portion of oral mucosal nevi that can be particularly insidious and misdiagnostic with the dreaded oral malignant melanoma (OMM).

For oral pigmented lesions and pigmented lesions at other parts of the body, the anatomo-pathological diagnosis consists of a morphological aspect (Hematoxylin-Eosin, H&E), an assessment using ancillary techniques of immunohistochemistry (IHC), and a increasingly active part of molecular biology. In this Research Topic, we aim to address this issue with contributions that shed light on these important aspects of oral pathology.

In this Research Topic, authors are invited to submit case reports, data reports, perspectives, general commentary, original articles and reviews relating to the pathological diagnosis of oral pigmented lesions at the dawn of 2023. Contributions relating to the field of molecular diagnostics applied to oral mucosa nevi/OMM are also welcome.

Keywords: Oral pathology, pigmented lesions, nevi, malignant melanoma, differential diagnosis


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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