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Over the last decade, there has been a significant increase in the interest of sleep research and how sleep affects human health. Compromised sleep quantity and/or quality can put an individual at a higher risk of many chronic conditions such as heart disease, dementia, or diabetes.
On average, human ...

Over the last decade, there has been a significant increase in the interest of sleep research and how sleep affects human health. Compromised sleep quantity and/or quality can put an individual at a higher risk of many chronic conditions such as heart disease, dementia, or diabetes.
On average, human sleep is composed of 90-minute cycles, each composed of 4 distinct stages. Stage 3 is often termed as sleep or slow-wave sleep and it is thought to be the most restorative and “deep sleep.” This stage is characterized by relative body immobility and low frequency, high amplitude semi rhythmic delta waves accounting for at least 20% of the EEG activity.
The role of slow wave sleep in memory consolidation has been widely documented however recent evidence shows an association between reduced slow wave sleep activity and chronic neurological conditions such as Alzheimer's and physiological conditions such as diabetes. The onset of slow wave sleep is temporally associated with changes in the metabolic, hormonal, and neurophysiological changes all of which if dysregulated by disruptions in slow wave sleep could significantly contribute to a wide range of chronic conditions onset, maintenance, and symptomatology. Despite recent advances, multiple aspects still need to be addressed for a complete understanding of slow wave sleep and chronic conditions.
 
Goal 
In this Research Topic, Frontiers in Sleep is looking to address key aspects of slow wave sleep in chronic diseases, symptom expression, and health in order to promote the discussion around this topic and to facilitate knowledge dissemination. 
 
Scope and information for Authors
We particularly welcome submission of Original Research, Review, Methods, and Perspective articles on the following sub-topics: 

1. The role of slow wave sleep in chronic diseases and pathophysiology.
2. Physiologic measures relevant to understanding slow wave sleep in chronic disease.
3. Interventions to improve slow wave sleep and their effects on disease pathophysiology and health. 
4. Slow wave sleep and health disparities
5. Slow wave sleep and healthy cognitive aging
6. Slow wave sleep and neurodegenerative disorders
7. Slow wave sleep and mental health 
8. Mechanisms of slow wave sleep in somatic symptoms expression
9. Slow wave sleep and chronic pain
10. Slow wave sleep and hypertension
11. Slow wave sleep and diabetes
12. Slow wave sleep and autoimmune-related disorders

Keywords: slow wave sleep, health


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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