About this Research Topic
In the era of technological advancement and innovative sciences, nanoparticles are considered as the front-runner. Nanomaterials are involved in numerous fields including energy, aviation, and agriculture. Over the past decade, nanoparticles have played a crucial role and stand accountable for the present progression in the biomedical sector including but not limited to targeted drug delivery and imaging. It would not be a hyperbole to say that drug targeted therapy has been one of the critical endeavors of the century. Since inception of the 1st generation controlled-release drug delivery system, nanotechnology has proven to be a vital platform and maneuvers crosstalk between biological and material science by producing various kinds of nanocarriers, including inorganic nanoparticles, polymeric nanoparticles, hydrogels, smart nanomaterials and many others for safe and efficient delivery of molecules to the targeted locations. Evidently, nanotechnology overcomes the limitations of conventional therapeutics like solubility, therapeutic index, toxicity, pH change, external environment degradation, and non-specific localization of drugs and even carries therapeutics to inaccessible locations such as those in the brain. Since, nanobiotechnology is a dynamic field, newer kind of nanomaterials are presented every day. Therefore, it is important to stay current with nanomaterials in relation to nanobiotechnology.
Implementation of a material for biomedical importance and clinical translations is highly determined by their proficiency in interacting, influencing, and regulating the cellular physiology and functioning. In this context, constant efforts are underway to develop advanced materials and approaches for efficient biomodulation. In the current scenario, nanoparticles have emerged as a persuasive contender with noteworthy contributions toward the advancement in the field of biomedical sciences. Biomodulation through nanoparticle interactions have become an exceptionally prevalent strategy for developing implants and scaffolds. This is particularly true in the development of dental treatments, wherein photobiomodulation therapy (PBMT) is increasingly used for periodontic, restorative, and prosthetic dentistry to treat peri-implant disease. The use of PBMT has been demonstrated to reduce postoperative dental pain, increase anesthesia depth, improve tooth hypersensitivity, reduce inflammation, and speed wound healing. Judiciously regulating the parameters for nanoparticle synthesis and adequate functionalization strategies could result in substantial outcomes along with application-based specificities. Innovation in the field of nanoparticle-based biomodulation have proffered the luxury to regulate immunological behavior of biological systems that could result in augmented tissue regeneration with minimal cellular toxicity.
The Research Topic welcomes manuscript from vast areas of nanomaterials in biological system, that include but are not limited to, nanoformulations for dental diseases, nanoformulations for theranostics and drug delivery techniques. We will also accept manuscripts with potential pathways to target or modulate biological functions.
Areas of study welcomed in this Research Topic include, but are not limited to:
• Investigation of innovative nanoparticles based biomodulation
• Fundamental aspects of nanoparticles synthesis approaches and their response upon interactions with biological system and cellular microenvironment
• Development of stimuli responsive biomodulations
• Biomodulation as a tool for nanoparticle applications in tissue engineering, drug delivery, biosensing, and regenerative medicine
• Photo-biomodulation (PBM) therapy for treatment of peri-implant disease
Implementation of a material for biomedical importance and clinical translations is highly determined by their proficiency in interacting, influencing, and regulating the cellular physiology and functioning. In this context, constant efforts are underway to develop advanced materials and approaches for efficient biomodulation. In the current scenario, nanoparticles have emerged as a persuasive contender with noteworthy contributions toward the advancement in the field of biomedical sciences. Biomodulation through nanoparticle interactions have become an exceptionally prevalent strategy for developing implants and scaffolds. This is particularly true in the development of dental treatments, wherein photobiomodulation therapy (PBMT) is increasingly used for periodontic, restorative, and prosthetic dentistry to treat peri-implant disease. The use of PBMT has been demonstrated to reduce postoperative dental pain, increase anesthesia depth, improve tooth hypersensitivity, reduce inflammation, and speed wound healing. Judiciously regulating the parameters for nanoparticle synthesis and adequate functionalization strategies could result in substantial outcomes along with application-based specificities. Innovation in the field of nanoparticle-based biomodulation have proffered the luxury to regulate immunological behavior of biological systems that could result in augmented tissue regeneration with minimal cellular toxicity.
The Research Topic welcomes manuscript from vast areas of nanomaterials in biological system, that include but are not limited to, nanoformulations for dental diseases, nanoformulations for theranostics and drug delivery techniques. We will also accept manuscripts with potential pathways to target or modulate biological functions.
Areas of study welcomed in this Research Topic include, but are not limited to:
• Investigation of innovative nanoparticles based biomodulation
• Fundamental aspects of nanoparticles synthesis approaches and their response upon interactions with biological system and cellular microenvironment
• Development of stimuli responsive biomodulations
• Biomodulation as a tool for nanoparticle applications in tissue engineering, drug delivery, biosensing, and regenerative medicine
• Photo-biomodulation (PBM) therapy for treatment of peri-implant disease
Keywords: nanoparticles, biomaterials, biomodulator, theranostics, antimicrobial photodynamic therapy (APDT), photobiomodulation therapy, PBMT, periodontics, peri-implant disease
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
