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About this Research Topic

Manuscript Submission Deadline 30 November 2023
Manuscript Extension Submission Deadline 31 December 2023

Biosensors have attracted great attention as a hot topic of analytical chemistry due to the low-cost, flexible design, and high specificity. Recently, emerging signal amplification techniques, including enzyme-assisted circuits, enzyme-free nucleic acid circuits, and micro/nano-material-based strategies have proven to be integrated with the biosensor for ultrasensitive analysis. Besides, advanced manufacturing techniques for the microelectrodes and micro-nano structure-based fiber optics have made single-cell sized biosensors become possible. Due to those efforts, biosensors have become a powerful tool for clinical diagnosis, food security, and basic research of life science.

This research topic aims to collect the highly sensitive and miniature biosensors. To be specific, it contains novel design principles, signal amplification strategies, integrated systems, and the corresponding application on real samples. The types of biosensors cover fiber optic-based, fluorescent, electrochemical, and colorimetric biosensors. The analytical targets are ranging from cancer cells to foodborne pathogens, neurotransmitters, proteins, metal ions, fungal toxins, and nucleic acids. The application fields include in vitro point-of-care testing, cell imaging, and implanted analysis of cells, tissues, or organs.

The topic editors hope to promote the development of biosensors and kindly welcome researchers to submit Original Research articles, Reviews, and Perspectives on the following themes that include but not limited to:
• The design principles of the fiber optic-based, fluorescent, electrochemical, and colorimetric biosensors;
• The novel signal amplification strategies for biosensors;
• The portable or miniature devices for the biosensor;
• The application of the biosensor for in vitro and in vivo analysis.

Keywords: fiber optic, fluorescent biosensor, electrochemical biosensor, colorimetry, signal amplification, biomarker detection.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Biosensors have attracted great attention as a hot topic of analytical chemistry due to the low-cost, flexible design, and high specificity. Recently, emerging signal amplification techniques, including enzyme-assisted circuits, enzyme-free nucleic acid circuits, and micro/nano-material-based strategies have proven to be integrated with the biosensor for ultrasensitive analysis. Besides, advanced manufacturing techniques for the microelectrodes and micro-nano structure-based fiber optics have made single-cell sized biosensors become possible. Due to those efforts, biosensors have become a powerful tool for clinical diagnosis, food security, and basic research of life science.

This research topic aims to collect the highly sensitive and miniature biosensors. To be specific, it contains novel design principles, signal amplification strategies, integrated systems, and the corresponding application on real samples. The types of biosensors cover fiber optic-based, fluorescent, electrochemical, and colorimetric biosensors. The analytical targets are ranging from cancer cells to foodborne pathogens, neurotransmitters, proteins, metal ions, fungal toxins, and nucleic acids. The application fields include in vitro point-of-care testing, cell imaging, and implanted analysis of cells, tissues, or organs.

The topic editors hope to promote the development of biosensors and kindly welcome researchers to submit Original Research articles, Reviews, and Perspectives on the following themes that include but not limited to:
• The design principles of the fiber optic-based, fluorescent, electrochemical, and colorimetric biosensors;
• The novel signal amplification strategies for biosensors;
• The portable or miniature devices for the biosensor;
• The application of the biosensor for in vitro and in vivo analysis.

Keywords: fiber optic, fluorescent biosensor, electrochemical biosensor, colorimetry, signal amplification, biomarker detection.


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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