About this Research Topic
This Research Topic is part of the Methods and Protocols in Toxicology series. Other titles in this series are:
• Methods and Protocols in Clinical Toxicology: 2023
• Methods and Protocols in Regulatory Toxicology: 2023
• Methods and Protocols in Neurotoxicology: 2023
Please submit your article to the Research Topic that best suits the focus of your research.
Introduction and general guidelines
This series aims to highlight the latest experimental methods and protocols in immunotoxicology, particularly methods that minimize or remove the need for animal testing. Review articles or opinions on methodologies or applications including the advantages and limitations of each are welcome. This Topic includes technologies and up-to-date methods which help advance science.
The contributions to this collection will undergo peer-review. Novelty may vary, but the utility of a method or protocol must be evident. We welcome contributions covering all aspects of immunotoxicology. Submissions will be handled by the team of Topic Editors in the respective sections.
Immunotoxicology guidelines
Over the past years, significant progresses have been made regarding the use of in vitro tests to identify chemicals and drugs altering immune functions and increasing sensitivity to cancers, autoimmune diseases and infections. Nevertheless, these bioassays require to be revitalized from the tremendous advancements in fundamental immunology and cell biology.
This Research Topic on Methods and Protocols is dedicated to environmental and clinical immunotoxicology. We are specifically looking for:
• Reviews highlighting the interests and limits of current in vitro tests used to predict chemical, pollutant and drug immunotoxicity.
• New in vitro or in silico methods/protocols applying immune receptors and sensors, discrete leukocyte populations or novel cytokines, chemokines and danger signals.
• Perspectives on implementation of genetics, epigenetics, proteomics, bioinformatics and system biology for evaluating immune hazard.
• Commentaries/Advances subject-based alerts on new concepts and techniques arising from basic immunology that can be translated in new immune bioassays and mode of actions.
• Systematic reviews identifying gaps and research needs in predictive immunotoxicity.
• New AOP (Adverse Outcome Pathway) articles detailing mechanistic evidence of chemical-induced sensitization, inflammation or immunosuppression.
• Guidelines and recommendations for how to (i) use generated data for risk evaluation and (ii) validate new methods that remain confined in research laboratories.
• Methods and Protocols in Clinical Toxicology: 2023
• Methods and Protocols in Regulatory Toxicology: 2023
• Methods and Protocols in Neurotoxicology: 2023
Please submit your article to the Research Topic that best suits the focus of your research.
Introduction and general guidelines
This series aims to highlight the latest experimental methods and protocols in immunotoxicology, particularly methods that minimize or remove the need for animal testing. Review articles or opinions on methodologies or applications including the advantages and limitations of each are welcome. This Topic includes technologies and up-to-date methods which help advance science.
The contributions to this collection will undergo peer-review. Novelty may vary, but the utility of a method or protocol must be evident. We welcome contributions covering all aspects of immunotoxicology. Submissions will be handled by the team of Topic Editors in the respective sections.
Immunotoxicology guidelines
Over the past years, significant progresses have been made regarding the use of in vitro tests to identify chemicals and drugs altering immune functions and increasing sensitivity to cancers, autoimmune diseases and infections. Nevertheless, these bioassays require to be revitalized from the tremendous advancements in fundamental immunology and cell biology.
This Research Topic on Methods and Protocols is dedicated to environmental and clinical immunotoxicology. We are specifically looking for:
• Reviews highlighting the interests and limits of current in vitro tests used to predict chemical, pollutant and drug immunotoxicity.
• New in vitro or in silico methods/protocols applying immune receptors and sensors, discrete leukocyte populations or novel cytokines, chemokines and danger signals.
• Perspectives on implementation of genetics, epigenetics, proteomics, bioinformatics and system biology for evaluating immune hazard.
• Commentaries/Advances subject-based alerts on new concepts and techniques arising from basic immunology that can be translated in new immune bioassays and mode of actions.
• Systematic reviews identifying gaps and research needs in predictive immunotoxicity.
• New AOP (Adverse Outcome Pathway) articles detailing mechanistic evidence of chemical-induced sensitization, inflammation or immunosuppression.
• Guidelines and recommendations for how to (i) use generated data for risk evaluation and (ii) validate new methods that remain confined in research laboratories.
Keywords: #Collectionseries, Environmental immunotoxicology, Clinical immunotoxicology, Immunotoxicity, Immunosuppression, Methods, Protocols
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
