Indication, Techniques and Innovations in Targeted Prostate Biopsy and Treatment

Prostate biopsy represents the gold standard diagnostic technique for the detection of prostate cancer. The use of magnetic resonance imaging (MRI)-transrectal ultrasound (TRUS) fusion prostate biopsy is associated with improved diagnostic accuracy as compared to standard TRUS guided biopsy. Transrectal and transperineal biopsy techniques as well as different fusion software platforms display unique advantages and disadvantages. Better identification of the index lesion has paved the way for targeted focal treatments to attempt to cure prostate cancer with less morbidity.
We aim to give an overview on biopsy techniques, fusion software platforms and novel (robotic) technologies. We will describe the role of prebiopsy imaging, biopsy templates and optimal biopsy strategies in order to improve detection of clinically relevant cancers and to avoid detection of indolent cancer. We will explore the role of focal therapy and other targeted treatments to reduce the morbidity of intervention while achieving optimal cancer control. The role of various energy sources and treatment strategies will also be discussed.
Sub-themes include, but are not limited to:
prebiopsy stratification; imaging protocols / optimization / 3D models; biopsy approaches, novel (robotic) techniques, fusion platforms; biopsy and sampling strategies; practice patterns worldwide (anaesthesia, antibiotics, settings); focal therapy energy sources; delivery techniques; peri-operative management; surveillance protocols; oncological and functional outcomes.

Keywords: Biopsy, Prostate, Diagnostics, Technique, Templates, Focal Therapy, Treatment

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