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About this Research Topic

Manuscript Submission Deadline 12 July 2023

Human brain organoid-on-a-chip (HBOOAC) models have been widely employed to investigate brain injuries, revolutionizing conventional paradigms in basic and clinical research, due to their advantages in simulating neurological damages in a 3D in vivo environment. In this regard, these HBOOAC models provide unique conditions for scrutinizing molecular pathological process and associated treatment of brain injuries. Substantial progress on the applications of these HBOOAC models has been primely made in basic research, whereas the applications in brain injury rehabilitation require further decoding.

This Research Topic aims to present and disseminate recent advances in the applications of HBOOAC models in molecular mechanisms during brain damage recovery, which entails key pathogenic factors, innovative modeling techniques, and novel treatment methods (e.g., biomaterials) in the pathological process of brain injuries.

This Research Topic welcomes submissions of Original Research and Review articles, along with Report, Data Report, Hypothesis & Theory, Methods, Mini Review, and Study Protocol. Themes of interest for publication include, but are not limited to:

• Molecular mechanisms of actions in brain injuries
• Development and applications of HBOOAC models in brain injuries
• Bibliometric investigation in neuroscience-related fields using HBOOAC models
• Development and applications of new regulation methods in brain injuries
• Development and applications of new biomaterials in brain injuries and nerve regenerative medicine

Chunping Qiao is affiliated with the REGENXBIO Inc, Rockville, MD 20850. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Keywords: Brain organoids, Models, Brain injury, Neuroregeneration, Bibliometric study


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Human brain organoid-on-a-chip (HBOOAC) models have been widely employed to investigate brain injuries, revolutionizing conventional paradigms in basic and clinical research, due to their advantages in simulating neurological damages in a 3D in vivo environment. In this regard, these HBOOAC models provide unique conditions for scrutinizing molecular pathological process and associated treatment of brain injuries. Substantial progress on the applications of these HBOOAC models has been primely made in basic research, whereas the applications in brain injury rehabilitation require further decoding.

This Research Topic aims to present and disseminate recent advances in the applications of HBOOAC models in molecular mechanisms during brain damage recovery, which entails key pathogenic factors, innovative modeling techniques, and novel treatment methods (e.g., biomaterials) in the pathological process of brain injuries.

This Research Topic welcomes submissions of Original Research and Review articles, along with Report, Data Report, Hypothesis & Theory, Methods, Mini Review, and Study Protocol. Themes of interest for publication include, but are not limited to:

• Molecular mechanisms of actions in brain injuries
• Development and applications of HBOOAC models in brain injuries
• Bibliometric investigation in neuroscience-related fields using HBOOAC models
• Development and applications of new regulation methods in brain injuries
• Development and applications of new biomaterials in brain injuries and nerve regenerative medicine

Chunping Qiao is affiliated with the REGENXBIO Inc, Rockville, MD 20850. All other Topic Editors declare no competing interests with regards to the Research Topic subject.

Keywords: Brain organoids, Models, Brain injury, Neuroregeneration, Bibliometric study


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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