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Statistics has shown that the number of elderly people over 65 reached 700 million worldwide in 2019, and China has become the country with the largest elderly population in the world. By 2021, the number of elderly people over 65 years old in China reached 190 million, accounting for 13.5 percent of the ...

Statistics has shown that the number of elderly people over 65 reached 700 million worldwide in 2019, and China has become the country with the largest elderly population in the world. By 2021, the number of elderly people over 65 years old in China reached 190 million, accounting for 13.5 percent of the total population, and the incidence of osteoporosis in this group of people was more than 60 percent. In the meantime, the prevalence of neurological diseases increases with age. Hip fractures are a common trauma in the elderly, and falls are the leading cause, often accompanied by endocrine system diseases such as diabetes, thyroid disease and osteoporosis. In recent years, the number of elderly patients with hip fractures accompanied by neurological diseases is raising. How to properly diagnose and treat these patients has become a difficult problem in clinical work.

Neurological diseases, such as Parkinson's disease (PD), are a group of neurodegenerative disorders characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta of the midbrain. Clinical manifestations are usually insidious, including tremor, bradykinesia, ankylosis contracture, dystonia, and postural flexion. Spasticity, tremor, and contracture often cause excessive muscle tension around the hip joint, making it prone to dislocation and aseptic loosening after hip replacement. In addition, people with Parkinson's disease are prone to persistent falls and have a significantly increased risk of fractures.

Therefore, neurological conditions affect hip stability, posing a considerable challenge in replacement surgery. However, total hip replacement (THR) was rarely performed in such patients in the past because it was considered a contraindication. How to break through this shackle is an urgent problem for orthopaedic doctors to solve.

The Research Topic invites submissions that offer new ideas and approaches for the treatment of hip fractures with neurological disorders. We welcome Original Research and Review articles on the following themes, including but not limited to basic research, clinical research, development and application of translational medicine, concise reviews, systemic reviews, and meta-analyses, commentaries and viewpoints:
- Effect of glucose variability on cerebral neurovascular disease in patients undergoing hip replacement
- Cortisol rhythm in hip arthroplasty patients with cerebral neurovascular disease
- Specific or medical treatment of elderly hip arthroplasty patients with cerebral neurovascular disease
- Reassessment of complications after hip arthroplasty in patients with neuromuscular diseases
- Selecting the appropriate implant for patients with cerebral neurovascular disease
- The risk of revision in patients with Parkinson’s disease

Keywords: hip arthroplasty, cerebral neurovascular disease, complication, revision, Parkinson’s disease


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