About this Research Topic
Frontiers in Systems Biology is a multidisciplinary open-access journal at the forefront of disseminating and communicating scientific knowledge and impactful discoveries in Systems Biology research to a broad community of researchers, academics, clinicians, and other relevant stakeholders.
Research in biology and biomedicine is tackling more complex questions than ever before, due to the seemingly intractable nature of the urgent questions affecting us all. Addressing these issues requires an integrated, interdisciplinary approach, and yet much of research in the field of biology remains entrenched in silos based on distinct disciplines and methods. Frontiers in Systems Biology seeks to change this through integration and collaboration across disciplines in the application Systems Research.
This journal serves as a unique and reliable repository of applicable research to better our understanding of life’s big questions.
This Research Topic is dedicated to collecting forward-looking articles composed by the Chief Editors of the journal. These contributions will identify and reflect upon what could be dubbed the “grand challenges” in Systems Biology research in the following specialties:
- Multiscale Mechanistic Modelling: This section highlights advances in computational modeling across biological scales
- Data and Model Integration: Section features the emerging field of ‘omics integration as well as studies in which data-driven and mechanistic models combine to drive novel insights
- Translational Systems Biology and In Silico Trials: Seeks to integrate disease modeling, quantitative systems pharmacology, and systems medicine to drive novel insights from bench to bedside
- Integrative Genetics and Genomics: Focuses on the application of systems biology to gain insights into the genome
- Integrative Systems Immunology: Highlights systems-level studies of immunology and inflammation
- Integrative Systems Neuroscience: Focuses on mechanistic multiscale neural and neural tissue simulations
Research in biology and biomedicine is tackling more complex questions than ever before, due to the seemingly intractable nature of the urgent questions affecting us all. Addressing these issues requires an integrated, interdisciplinary approach, and yet much of research in the field of biology remains entrenched in silos based on distinct disciplines and methods. Frontiers in Systems Biology seeks to change this through integration and collaboration across disciplines in the application Systems Research.
This journal serves as a unique and reliable repository of applicable research to better our understanding of life’s big questions.
This Research Topic is dedicated to collecting forward-looking articles composed by the Chief Editors of the journal. These contributions will identify and reflect upon what could be dubbed the “grand challenges” in Systems Biology research in the following specialties:
- Multiscale Mechanistic Modelling: This section highlights advances in computational modeling across biological scales
- Data and Model Integration: Section features the emerging field of ‘omics integration as well as studies in which data-driven and mechanistic models combine to drive novel insights
- Translational Systems Biology and In Silico Trials: Seeks to integrate disease modeling, quantitative systems pharmacology, and systems medicine to drive novel insights from bench to bedside
- Integrative Genetics and Genomics: Focuses on the application of systems biology to gain insights into the genome
- Integrative Systems Immunology: Highlights systems-level studies of immunology and inflammation
- Integrative Systems Neuroscience: Focuses on mechanistic multiscale neural and neural tissue simulations
Keywords: Grand Challenge, Systems Biology
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
