About this Research Topic
“A Year in Review: Discussions in Human and Medical Genomics” is part of a wider series of Research Topics across Frontiers in Genetics, hosted by our Specialty Chief Editors and esteemed Associate Editors.
This Research Topic aims to spark discussion around popular articles from 2022 in Human and Medical Genomics. This field is continuously evolving, therefore we are seeking to understand developments and perspectives on articles that have attracted attention throughout the year.
The chosen manuscripts are:
• Imputation Performance in Latin American Populations: Improving Rare Variants Representation With the Inclusion of Native American Genomes
• A Polygenic Score for Type 2 Diabetes Improves Risk Stratification Beyond Current Clinical Screening Factors in an Ancestrally Diverse Sample
• Whole Blood Transcriptome Analysis in Children with Sickle Cell Anemia
• Prevalence of Clinically Relevant Germline BRCA Variants in a Large Unselected South African Breast and Ovarian Cancer Cohort: A Public Sector Experience
• The Impact of Proband Indication for Genetic Testing on the Uptake of Cascade Testing Among Relatives
We welcome Opinions, Perspectives, Hypotheses and Theory, and Mini-Review article types to facilitate this discussion. Please note, only relevant papers that add a significant contribution to the discussion articles will be considered.
This Research Topic aims to spark discussion around popular articles from 2022 in Human and Medical Genomics. This field is continuously evolving, therefore we are seeking to understand developments and perspectives on articles that have attracted attention throughout the year.
The chosen manuscripts are:
• Imputation Performance in Latin American Populations: Improving Rare Variants Representation With the Inclusion of Native American Genomes
• A Polygenic Score for Type 2 Diabetes Improves Risk Stratification Beyond Current Clinical Screening Factors in an Ancestrally Diverse Sample
• Whole Blood Transcriptome Analysis in Children with Sickle Cell Anemia
• Prevalence of Clinically Relevant Germline BRCA Variants in a Large Unselected South African Breast and Ovarian Cancer Cohort: A Public Sector Experience
• The Impact of Proband Indication for Genetic Testing on the Uptake of Cascade Testing Among Relatives
We welcome Opinions, Perspectives, Hypotheses and Theory, and Mini-Review article types to facilitate this discussion. Please note, only relevant papers that add a significant contribution to the discussion articles will be considered.
Keywords: imputation, type 2 diabetes, risk stratification, whole blood transcriptome, sickle cell anemia, BRCA, cancer, breast, ovarian, genetic testing, cascade testing, polygenic risk score
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
