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About this Research Topic

Manuscript Submission Deadline 12 November 2023
Manuscript Extension Submission Deadline 17 December 2023

Type I collagen is the most abundant structural protein of vertebrates’ connective tissues whose structure almost unvaried during the millennia, suggesting its key role in maintaining and regulating tissues physiological structural integrity and biological functions. Biomaterials are the most widely used kind of material for the development of health-care related products. In particular, they are selected for the development of implantable devices meant to be used for the regeneration of injured tissues, following the principles of Tissue Engineering and Regenerative Medicine for their advantageous properties. In recent years, biomaterials-based injectable products have been even more used for – but not limited to – the treatment of different kind of age-related diseases. Accordingly, several types of formulations were designed, optimized, and enriched with bioactive compounds in order to improve collagen products’ efficacy. Thus, the aim of this Special Issue will be the harvesting of the most recent trends and findings on the development and use of biomaterials-based injectable products for the treatment of diseases of the following apparatus:

· Integumental
· Gastrointestinal
· Musculoskeletal
· Urogenital

The present Research Topic will welcome contributions in the form of original article, clinical studies, and review articles.

Keywords: Type I collagen, Bioactive compounds, Biomaterials, Tissue Regeneration, Collagen-based injectable products


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Type I collagen is the most abundant structural protein of vertebrates’ connective tissues whose structure almost unvaried during the millennia, suggesting its key role in maintaining and regulating tissues physiological structural integrity and biological functions. Biomaterials are the most widely used kind of material for the development of health-care related products. In particular, they are selected for the development of implantable devices meant to be used for the regeneration of injured tissues, following the principles of Tissue Engineering and Regenerative Medicine for their advantageous properties. In recent years, biomaterials-based injectable products have been even more used for – but not limited to – the treatment of different kind of age-related diseases. Accordingly, several types of formulations were designed, optimized, and enriched with bioactive compounds in order to improve collagen products’ efficacy. Thus, the aim of this Special Issue will be the harvesting of the most recent trends and findings on the development and use of biomaterials-based injectable products for the treatment of diseases of the following apparatus:

· Integumental
· Gastrointestinal
· Musculoskeletal
· Urogenital

The present Research Topic will welcome contributions in the form of original article, clinical studies, and review articles.

Keywords: Type I collagen, Bioactive compounds, Biomaterials, Tissue Regeneration, Collagen-based injectable products


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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