About this Research Topic
Bioactive hydrogels are polymeric matrices that are characterized by having a high affinity for water adsorption, mimicking the extracellular matrices that make up mammalian tissues. In this sense, it is of vital importance to study the interactions of cells important in biomedical fields on this type of matrices, in order to design new biomaterials that can optimize their use in areas of tissue engineering. The main aim of this research topic is to address both the synthesis, characterization of structure and surface properties, and their evaluation of the in vitro or in vivo biological response of novel matrices in the hydrogel state that could have potential applications in the understanding of cellular interactions with this type of polymeric matrices, thus generating frontier knowledge that could be used to generate technology that could allow the design of new biomaterials with successful application in tissue repair.
The goal of this Research Topic is to try to propose a series of articles from various world research groups that cover the construction of biomatrices in a hydrogel state, the study of their physicochemical properties and biological evaluation using different types of cells with importance in biomedicine and tissue engineering. This will allow the generation of an informative compendium that allows the community interested in the field to understand how the composition, structure and physicochemical properties influence on cell behavior and can adapt cell activities, for the conception of novel biomatrices in the hydrogel state that can be used in strategies for tissue engineering.
We welcome the submission of manuscripts including, but not limited to, the following topics:
• Bioactive hydrogels for the study of cell-extracellular matrix interactions
- Study of cells of the immune system on hydrogels for wound healing
- Metabolism and proliferation of dermal cells growing on matrices in a hydrogel state for the design of new biomaterials that can be used as dressings for healing chronic wounds.
- Evaluation of the metabolism and proliferation of bone cells growing on hydrogels to obtain biomatrices that mimic the native structure of bone.
- Cellular differentiation promoted by materials in the hydrogel state.
• Generation of novel synthesis routes for biomatrix in the hydrogel state and the study of its structural and physicochemical properties that allow us to understand the cell-extracellular matrix interaction.
The goal of this Research Topic is to try to propose a series of articles from various world research groups that cover the construction of biomatrices in a hydrogel state, the study of their physicochemical properties and biological evaluation using different types of cells with importance in biomedicine and tissue engineering. This will allow the generation of an informative compendium that allows the community interested in the field to understand how the composition, structure and physicochemical properties influence on cell behavior and can adapt cell activities, for the conception of novel biomatrices in the hydrogel state that can be used in strategies for tissue engineering.
We welcome the submission of manuscripts including, but not limited to, the following topics:
• Bioactive hydrogels for the study of cell-extracellular matrix interactions
- Study of cells of the immune system on hydrogels for wound healing
- Metabolism and proliferation of dermal cells growing on matrices in a hydrogel state for the design of new biomaterials that can be used as dressings for healing chronic wounds.
- Evaluation of the metabolism and proliferation of bone cells growing on hydrogels to obtain biomatrices that mimic the native structure of bone.
- Cellular differentiation promoted by materials in the hydrogel state.
• Generation of novel synthesis routes for biomatrix in the hydrogel state and the study of its structural and physicochemical properties that allow us to understand the cell-extracellular matrix interaction.
Keywords: Biomatrix, hydrogel, cell-matrix interaction, tissue engineering
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
