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Electroanalytical chemistry combines basic principles and methods of electrochemistry and analytical chemistry for the qualitative and quantitative determination of abundant electrochemical information and processes, such as substance composition, electrode process dynamics, electrochemical reaction mechanism, and biosensing. Conventional electroanalytical chemistry methods barely present spatial resolution ability, which cannot characterize the information of different regions on the surface of one electrode. Electrochemical imaging methods can spatially resolved distinguish surface electrochemical activity of different micro areas, which were used to study the geometric morphology of the sample on the electrode surface, the redox activity between two-phase interface, electrochemical kinetics of microdomain, spatially resolved charge-transfer processes, and live cell imaging. Electrochemical imaging methods meet the development demands of analytical science and biosensor by high throughput detection and visualization of electrochemical information.

Electroanalytical Chemical Imaging can achieve spatially resolved electrochemical recordings, which can be adopted for the construction of sensor arrays and for biological imaging. Current electrochemical imaging methods include nanoarray electrodes, scanning electrochemical microscopy (SECM), scanning ion conductance microscopy (SICM), plasmonic-based electrochemical impedance microscopy (P-EIM), light-addressable potentiometric sensor (LAPS) imaging, light-addressable electrochemical sensor (LAES) imaging, and so on. A host of strategies and methodologies have been explored to enhance spatial resolution. Electrochemical imaging methods are still far from the maturity to realize fulfilling practical applications. In order to make it truly useful in biochemical imaging, sensor performances in terms of spatial-temporal resolution, sensor stability, repeatability and biocompatibility should be further investigated and improved. This requires multidisciplinary research and collaboration. We anticipate that the improved electrochemical imaging will be able to be used for multi purposes, including high-throughput drug screening, protein and gene chips, cell-based chips, or serving as a regular and universal platform for single living cell imaging and analysis.

Within this Research Topic, we aim to bring up to date the advances in electroanalytical chemical imaging. Submissions may include electrochemical imaging methods, the functionalization of sensing interfaces, the optimization of measurement electronics, and imaging data processing procedures.
• Development, discussion and enhancement of electroanalytical chemical imaging including nanoarray electrodes, SECM, SICM, P-EIM, LAPS imaging, LAES imaging, etc.
• Application of electrochemical imaging in biochemical applications including multiplexed detection, protein and gene chips, cell-based chips, or serving as a platform for single living cell imaging and analysis and so on.

Interested submissions include original research articles and review articles.

Keywords: Electroanalytical Chemistry, Chemical Imaging, Sensors, Resolution, Current


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Electroanalytical chemistry combines basic principles and methods of electrochemistry and analytical chemistry for the qualitative and quantitative determination of abundant electrochemical information and processes, such as substance composition, electrode process dynamics, electrochemical reaction mechanism, and biosensing. Conventional electroanalytical chemistry methods barely present spatial resolution ability, which cannot characterize the information of different regions on the surface of one electrode. Electrochemical imaging methods can spatially resolved distinguish surface electrochemical activity of different micro areas, which were used to study the geometric morphology of the sample on the electrode surface, the redox activity between two-phase interface, electrochemical kinetics of microdomain, spatially resolved charge-transfer processes, and live cell imaging. Electrochemical imaging methods meet the development demands of analytical science and biosensor by high throughput detection and visualization of electrochemical information.

Electroanalytical Chemical Imaging can achieve spatially resolved electrochemical recordings, which can be adopted for the construction of sensor arrays and for biological imaging. Current electrochemical imaging methods include nanoarray electrodes, scanning electrochemical microscopy (SECM), scanning ion conductance microscopy (SICM), plasmonic-based electrochemical impedance microscopy (P-EIM), light-addressable potentiometric sensor (LAPS) imaging, light-addressable electrochemical sensor (LAES) imaging, and so on. A host of strategies and methodologies have been explored to enhance spatial resolution. Electrochemical imaging methods are still far from the maturity to realize fulfilling practical applications. In order to make it truly useful in biochemical imaging, sensor performances in terms of spatial-temporal resolution, sensor stability, repeatability and biocompatibility should be further investigated and improved. This requires multidisciplinary research and collaboration. We anticipate that the improved electrochemical imaging will be able to be used for multi purposes, including high-throughput drug screening, protein and gene chips, cell-based chips, or serving as a regular and universal platform for single living cell imaging and analysis.

Within this Research Topic, we aim to bring up to date the advances in electroanalytical chemical imaging. Submissions may include electrochemical imaging methods, the functionalization of sensing interfaces, the optimization of measurement electronics, and imaging data processing procedures.
• Development, discussion and enhancement of electroanalytical chemical imaging including nanoarray electrodes, SECM, SICM, P-EIM, LAPS imaging, LAES imaging, etc.
• Application of electrochemical imaging in biochemical applications including multiplexed detection, protein and gene chips, cell-based chips, or serving as a platform for single living cell imaging and analysis and so on.

Interested submissions include original research articles and review articles.

Keywords: Electroanalytical Chemistry, Chemical Imaging, Sensors, Resolution, Current


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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