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About this Research Topic

Manuscript Submission Deadline 22 October 2023
Manuscript Extension Submission Deadline 29 February 2024

The microbiome, nutrition, and health. Developing novel therapeutic approaches that address physical activity, gut microbiota modulation by nutrients, and chronobiology in the context of both health and cancer.

Our microbiome plays an important role in maintaining our health. Numerous ...

The microbiome, nutrition, and health. Developing novel therapeutic approaches that address physical activity, gut microbiota modulation by nutrients, and chronobiology in the context of both health and cancer.

Our microbiome plays an important role in maintaining our health. Numerous non-communicable diseases have been linked to pathophysiological changes in the gut microbiota, including obesity, cancer, type 2 diabetes, cardiovascular disease, and metabolic syndrome. The role of microbiota in carcinogenesis has been established in several recent studies. Several factors have been identified as being affected by microbiota in cancer, including the contribution of microbiota to oncogenesis, the susceptibility to oncogenesis and its progression, the development of coinfections, and the response to anticancer treatment. Microbiota and their contribution to anticancer responses have motivated researchers to develop anticancer therapeutics based on microbes. Nutrients (dietary supplements) and habits (physical activity) may modulate the gut microbiota both in healthy individuals and in cancer patients. These changes are being investigated to fully understand their impact on the body with a particular focus on chronobiology.

This Research Topic aims to better understand the interaction between nutrition, physical activity, and changes in intestinal microbiota composition in health and cancer, focusing on chronobiology. To understand health and cancer within the context of vital variables such as chronobiology, clock genes, nutrition, dietary patterns, physical activity, and intestinal microbiota protocols, among others, it is necessary to correlate intestinal microbiota with nutritional patterns in human studies, as well as cancer studies implementing physical exercise programs or intestinal microbiota protocols.

This Research Topic welcomes Original Research, Reviews, Mini-reviews, and Perspectives on studies conducted in vitro, animal, and human models, including, but not limited to:
-The influence of changes in the composition of the microbiota on health and cancer
-Dietary habits and dysbiosis of the gut microbiota in cancer and health
-In relation to health or cancer, the effects of alternative traditional treatments on gut microbiota composition (physical exercise programs)
-How dietary components influence and modulate the gut microbiota in relation to health and cancer
-The effects of functional foods, probiotics, and synbiotics on the composition and structure of gut microbiota on the prevention of extraintestinal diseases.

Keywords: Physical exercise, Nutrition, Cancer, Chronobiology, Clock genes, Microbiota, Nutrient supplementation, Circadian rhythms


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