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Nutritional genomics research is consistently advancing, including pragmatic research evaluating the potential health and behavior change benefits of providing genetically tailored nutrition information/advice. In addition, multi-omics approaches are now contributing to our understanding of precision nutrition by providing evidence of biological plausibility for specific nutrigenetic interactions. However, many studies do not report their research in a manner that is suitable for knowledge translation and applications to clinical settings. In addition, systematic reviews with evidence grading and clinical practice guidelines in the field are almost non-existent. At the same time, we are seeing some practitioners and companies applying nutritional genomics research into clinical practice and direct-to-consumer genetic testing services.

Despite this uptake, there is a gap in knowledge about how existing original research may be implemented for clinical/consumer applications in an evidence-based manner. Thus, further research with a focus on translational nutritional genomics is urgently needed to help ensure that practitioners and industry are implementing this exciting science in an evidence-based manner.

The overarching goal of this article collection is to help bridge the gap between current knowledge in the field of nutritional genomics research and the clinical applicability and knowledge translation to healthcare professionals, industry, decision-makers, and the public. In addition, this collection aims to identify barriers, facilitators, and opportunities for knowledge translation and clinical applications. For example, opportunities may relate to the use of artificial intelligence/machine learning models or nutrigenetic risk scores to better understand the science of nutritional genomics and its clinical application.

In this Research Topic, we welcome original research, review articles, and commentaries in the field of nutritional genomics on themes including, but not limited to:
• Clinical & scientific validity
• Applications to clinical practice and/or direct-to-consumer genetic testing services
• Polygenic/nutrigenetic risk scores
• Knowledge and attitudes towards nutritional genomics
• Systematic reviews and/or clinical practice guidelines of specific gene-diet interactions, and/or bioinformatic predictive models

Any article relevant to the overarching topic of "translational nutritional genomics" will be considered.

Keywords: Nutrigenomics, Nutrigenetics, Omics, Nutritional genomics, Proteomics, Transcriptomics, Metabolomics, Microbiome, Knowledge translation, Clinical applications, Multi-omics


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Nutritional genomics research is consistently advancing, including pragmatic research evaluating the potential health and behavior change benefits of providing genetically tailored nutrition information/advice. In addition, multi-omics approaches are now contributing to our understanding of precision nutrition by providing evidence of biological plausibility for specific nutrigenetic interactions. However, many studies do not report their research in a manner that is suitable for knowledge translation and applications to clinical settings. In addition, systematic reviews with evidence grading and clinical practice guidelines in the field are almost non-existent. At the same time, we are seeing some practitioners and companies applying nutritional genomics research into clinical practice and direct-to-consumer genetic testing services.

Despite this uptake, there is a gap in knowledge about how existing original research may be implemented for clinical/consumer applications in an evidence-based manner. Thus, further research with a focus on translational nutritional genomics is urgently needed to help ensure that practitioners and industry are implementing this exciting science in an evidence-based manner.

The overarching goal of this article collection is to help bridge the gap between current knowledge in the field of nutritional genomics research and the clinical applicability and knowledge translation to healthcare professionals, industry, decision-makers, and the public. In addition, this collection aims to identify barriers, facilitators, and opportunities for knowledge translation and clinical applications. For example, opportunities may relate to the use of artificial intelligence/machine learning models or nutrigenetic risk scores to better understand the science of nutritional genomics and its clinical application.

In this Research Topic, we welcome original research, review articles, and commentaries in the field of nutritional genomics on themes including, but not limited to:
• Clinical & scientific validity
• Applications to clinical practice and/or direct-to-consumer genetic testing services
• Polygenic/nutrigenetic risk scores
• Knowledge and attitudes towards nutritional genomics
• Systematic reviews and/or clinical practice guidelines of specific gene-diet interactions, and/or bioinformatic predictive models

Any article relevant to the overarching topic of "translational nutritional genomics" will be considered.

Keywords: Nutrigenomics, Nutrigenetics, Omics, Nutritional genomics, Proteomics, Transcriptomics, Metabolomics, Microbiome, Knowledge translation, Clinical applications, Multi-omics


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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