About this Research Topic
Despite the remarkable improvement in the prevention and management of cardiovascular diseases and complications, the demand for novel solutions for the repair and regeneration of cardiac and vascular tissues is continuously rising.
These are exciting times for the study of materials for healthcare and the cardiovascular field is a highly relevant environment for the application of these new technologies. To date, material scientists are developing an increasing number of solutions and innovations for the diagnosis and therapy of cardiovascular diseases and their complication: new nanomaterials for biomarker detection, injectable gels and patches for cardiac repair, synthetic and natural solutions for vascular grafts.
New research has been focused on the role of cells, seeded on the materials or present within the tissue, in the reparative process and in the protection against adverse events connected to the interaction between biomaterials and living tissues. This includes the development of strategies to create an autologous endothelial tissue in contact with the artificial materials at the luminal surface of cardiovascular devices. The study of the cell and blood interaction with the materials and the development of novel ways of harnessing this potential by changing the material design are at the forefront of this field.
This Research Topic focuses on the recent developments of new nano and bio-materials for the improvement of cardiovascular outcomes and on the in-depth study of their interaction with cells and tissues.
In particular we encourage submissions in the following topics:
• Biomaterials and functionalizations for prosthesis and scaffolds (vascular grafts, cardiac/vascular valves, cardiac patches etc)
• Nanomaterials for imaging/detection/drug delivery relevant to the cardiovascular field
• Bio and nano-materials interactions with vascular, cardiac and immune cells
Keywords: nanomaterials, biomaterials, tissue engineering, cell/material interaction, bioscaffolds
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.