The tumor microenvironment (TME) plays a key role in cancer development and emergence of drug resistance. TME modulation has recently garnered attention as a potential approach for reprogramming the TME and resensitizing resistant neoplastic niches to existing cancer therapies such as immunotherapy or chemotherapy. Nano-based solutions have significant advantages over traditional platforms, such as the possibility of being specifically targeted and delivered to desired sites. There are numerous efforts ongoing for cancer diagnosis and treatment using optimized biomaterials. Some types of biomaterials are capable of intrinsically act as anticancer agents, while others can be used as drug delivery vehicles in targeted therapies on tumor cells. Targeting tumor microenvironments is another important application of anticancer materials, as it is a vital determinant of the final fate of cancer therapy. The microenvironment is increasingly recognized to have key roles in cancer, and biomaterials provide a means to engineer microenvironments, both in vitro and in vivo, to study and manipulate cancer.
This Research Topic will provide a valuable collection of contributions and a platform for a scientific discussion focused on biomaterials applications in the context of cancer therapy and tumor microenvironment modulation.
The key topic will include but not be limited to biomaterials types, synthesis, nature of biomaterials and its impact on tumor microenvironment, efficiency of biomaterial for delivering drug and biological agents to the tumor.
This Research Topic will welcome:
• Original research papers
• Short communications
• Meta-analysis
• Reviews
Keywords:
Nanotechnology, Material, Tumour, Tumour microenvironment, Cancer therapeutics.
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
The tumor microenvironment (TME) plays a key role in cancer development and emergence of drug resistance. TME modulation has recently garnered attention as a potential approach for reprogramming the TME and resensitizing resistant neoplastic niches to existing cancer therapies such as immunotherapy or chemotherapy. Nano-based solutions have significant advantages over traditional platforms, such as the possibility of being specifically targeted and delivered to desired sites. There are numerous efforts ongoing for cancer diagnosis and treatment using optimized biomaterials. Some types of biomaterials are capable of intrinsically act as anticancer agents, while others can be used as drug delivery vehicles in targeted therapies on tumor cells. Targeting tumor microenvironments is another important application of anticancer materials, as it is a vital determinant of the final fate of cancer therapy. The microenvironment is increasingly recognized to have key roles in cancer, and biomaterials provide a means to engineer microenvironments, both in vitro and in vivo, to study and manipulate cancer.
This Research Topic will provide a valuable collection of contributions and a platform for a scientific discussion focused on biomaterials applications in the context of cancer therapy and tumor microenvironment modulation.
The key topic will include but not be limited to biomaterials types, synthesis, nature of biomaterials and its impact on tumor microenvironment, efficiency of biomaterial for delivering drug and biological agents to the tumor.
This Research Topic will welcome:
• Original research papers
• Short communications
• Meta-analysis
• Reviews
Keywords:
Nanotechnology, Material, Tumour, Tumour microenvironment, Cancer therapeutics.
Important Note:
All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.