About this Research Topic
The interaction between nervous and immune systems is an important mechanism for maintaining health. Neuro-Immune interaction is mainly mediated by neurotransmitters, neuropeptides, and cytokines. Immune cells respond to neural signals by expressing receptors for nerve cell-derived molecules, and neurons, in turn, express receptors for immune-derived cytokines and neurotransmitters, which may affect neural function. Invading microorganisms produce molecular products to activate sensory neurons, generate action potentials and release corresponding neurotransmitters to regulate the immune system. Meanwhile, the immune system constantly feeds back information to neurons to modify control signals to achieve dynamic balance. More and more studies have shown that this kind of crosstalk occurs more frequently during infection than is realized. It has been confirmed that neuroimmune crosstalk coordinates physiological processes such as host defense, tissue repair and metabolism in the skin, intestines, lungs, and other organs. Identifying the interaction between these two complex systems is challenging, but contributes to our understanding of pathogenesis which may lead to new therapeutic interventions.
This Research Topic will focus on the mechanism of neuro-immune system interaction during infection, as well as the application of related technologies or products in disease treatment, to provide new strategies for the treatment of infection.
We welcome manuscripts focusing on, but are not limited to, the following subtopics,
1. Mechanism of microorganisms activating the nervous/immune system
2. The role of neuro-immunity in the pathogenesis of infection
3. Mutual regulation mechanism of neuro-immunity during infection
4. Drug or technology development based on neuro-immune regulation
5. Integration of multi-omics technologies to clarify the changes of microorganisms, immune system and nervous system during infection
This Research Topic will focus on the mechanism of neuro-immune system interaction during infection, as well as the application of related technologies or products in disease treatment, to provide new strategies for the treatment of infection.
We welcome manuscripts focusing on, but are not limited to, the following subtopics,
1. Mechanism of microorganisms activating the nervous/immune system
2. The role of neuro-immunity in the pathogenesis of infection
3. Mutual regulation mechanism of neuro-immunity during infection
4. Drug or technology development based on neuro-immune regulation
5. Integration of multi-omics technologies to clarify the changes of microorganisms, immune system and nervous system during infection
Keywords: infection, nervous system, immune system
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
