The craniofacial complex comprises the most intricate anatomical structures in the human body. Developmental defects, traumatic injury, or neoplastic tissue formation can directly affect the functional and aesthetic intricacies of the face and cranium. While reconstructive and aesthetic surgical techniques have long been innovated in this field, there are crucial limitations to the surgical restoration of craniomaxillofacial form and function.
Fortunately, the rise of regenerative medicine and surgery has expanded the possibilities for patients affected with hard and soft tissue deficits. Regenerative medicine applied to reconstructive surgery of the craniomaxillofacial complex has allowed for the controlled engineering and regeneration of patient-specific defects. Innovative advances made in biomedical engineering, including scaffold-based delivery systems for precision tissue engineering, now offer new avenues for stimulating bone and soft-tissue formation at the site of the surgical correction of deficient craniofacial anatomy.
This Special Topic aims to highlight the regenerative concepts currently explored in the pre-clinical and clinical realm for functional and aesthetic restoration of the craniomaxillofacial complex. We invite researchers (clinicians, scientists, engineers) in the fields of plastic and reconstructive surgery, oral and maxillofacial surgery, otolaryngology—head and neck surgery, and neurosurgery to contribute original articles, reports, or reviews to this Special Issue of Frontiers in Surgery.
We look forward to receiving your submissions!
Keywords: Craniomaxilliofacial, Reconstruction, Surgery, Regenerative, soft-tissue
Important note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
