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About this Research Topic

Manuscript Submission Deadline 27 November 2023
Manuscript Extension Submission Deadline 27 December 2023

Gestational diabetes (GDM) affects 1 out of 6 pregnancies globally, and is associated with adverse pregnancy outcomes, including pre-eclampsia, preterm birth, stillbirth, large for gestational age, and increased risk of future diabetes in mother and child. Because of this, international and national ...

Gestational diabetes (GDM) affects 1 out of 6 pregnancies globally, and is associated with adverse pregnancy outcomes, including pre-eclampsia, preterm birth, stillbirth, large for gestational age, and increased risk of future diabetes in mother and child. Because of this, international and national guidelines recommend routine screening for GDM in all pregnant women. However, data suggest that settings tend to prioritize “high-risk” women, at best, leading to a limited understanding of the epidemiology, diagnosis, pathogenesis, and management of populations with non-traditional risk factors for GDM.

The diagnosis and management of GDM is globally inconsistent. In this Research Topic, we hope to solicit novel research from around the world to update the current understanding of the epidemiology, pathogenesis, diagnostic criteria, management, short- and long-term outcomes of women with GDM and their infants, and evidence for diabetes prevention in women with GDM.

Specific themes of interest include:

• Epidemiology of GDM, including novel risk factors, racial disparities, low BMI populations

• Pathogenesis of gestational diabetes in different populations or subgroups (e.g. people living with HIV, non-obese)

• Innovative testing approaches and diagnostic criteria for GDM

• Novel approaches to GDM management (pharmacologic and nonpharmacologic)

• Short- and long-term pregnancy, maternal, infant, and childhood outcomes associated with GDM

• GDM as an opportunity for prevention of T2DM (for mother and infant)

• Effect of GDM on immune function, with a focus on the risk of infections (e.g. COVID) and vaccine efficacy in mothers and infants.

• Cost-effectiveness of diagnosis and treatment of GDM in different populations (short-term and long-term)

• Qualitative studies focused on GDM

Keywords: Gestational diabetes, epidemiology, diagnosis, management, outcomes, pathogenesis, controversies


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