About this Research Topic
To understand the host defence mechanisms during viral infections, immunologists and virologists have been approaching host-pathogen interactions from different angles. In the immunology field, it is perceived that the host response induced after being exposed to infectious diseases or vaccination is multidimensional and differs depending on the nature of the exposure, i.e., the pathogen type or the vaccine type, including the delivery system. Likewise, a differential response of immune cells depending on their location in distinct organs is appreciated. By contrast, in the virology field, research interests are mostly skewed towards the innate immune responses and antibody production, but a deep understanding of the adaptive immune response is often missing.
In this collection, we look to incorporate scientific pieces that address in depth the adaptive immune responses induced during respiratory viral infections and after vaccination against respiratory viruses. Since the adaptive immune responses involved in the host defense are a combination of migration and activation of multiple immune cells at different stages of infection, we would like to focus on: a) Immune cells’ differentiation and characteristics of different cellular populations, b) specific functions of immune cells, and cytokines/chemokines involved in immune cell activation, and c) the memory immune response, with a main focus on the generation and function of memory immune cells induced. We consider that by understanding how the host adaptive immune system functions during respiratory viral infections, we can contribute to the design of vaccines that induce specific functional immune cells at the local sites of infection.
The scope of this topic includes the following:
• Virus infection and adaptive immunity
• Virus specific T cells/ B cells
• Vaccine Immunology
• Immune memory
• Tissue specific memory cells
In this collection, we look to incorporate scientific pieces that address in depth the adaptive immune responses induced during respiratory viral infections and after vaccination against respiratory viruses. Since the adaptive immune responses involved in the host defense are a combination of migration and activation of multiple immune cells at different stages of infection, we would like to focus on: a) Immune cells’ differentiation and characteristics of different cellular populations, b) specific functions of immune cells, and cytokines/chemokines involved in immune cell activation, and c) the memory immune response, with a main focus on the generation and function of memory immune cells induced. We consider that by understanding how the host adaptive immune system functions during respiratory viral infections, we can contribute to the design of vaccines that induce specific functional immune cells at the local sites of infection.
The scope of this topic includes the following:
• Virus infection and adaptive immunity
• Virus specific T cells/ B cells
• Vaccine Immunology
• Immune memory
• Tissue specific memory cells
Keywords: Respiratory virus infection, Vaccine, Adaptive immune response, Tissue-specific immune response
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
