About this Research Topic
Nucleic acids analysis (genomics) is used in applications that require genetic identification, genotyping, gene expression, species identification and more. It includes isolation and characterization/identification of DNA/RNA specific sequences. Nucleic acids, DNA in particular, are usually the analyte of choice due to enhanced stability especially under acute circumstances, as well as high selectivity and specificity among closely related species. Furthermore, nucleic acids analysis are not affected by alternation in environmental conditions. Nucleic acid-based methods provide high sensitivity, robustness and specificity and have been widely applied for the analysis of clinical, environmental and food samples, as well as pathogens and biomarkers detection and animal- and/or plant-species identification.
The amount and the quality of the isolated genetic material is very crucial for the effective performance of nucleic acid-based methods. Moreover, new analytical methods are required that provide fast analysis with high detectability, sensitivity and specificity. In this context, innovative analytical devices and biosensors with enhanced analytical performance, along with potential portability and ease of use are in the forefront. New materials are also exploited as reporters to enhance the detectability of the methods and devices. Innovative protocols are developed for target recycling and/or signal enhancement to increase the detectability and the sensitivity of the methods. In addition, simple and cost-effective analytical devices and biosensors are needed to provide rapid analysis, without requiring qualified personnel for their performance.
We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:
• Analytical methods for nucleic acids analysis
• Novel target amplification and non-amplification techniques
• Analytical devices and biosensors for nucleic acids analysis
• Rapid methods, analytical devices and biosensors for nucleic acids analysis
• Electrochemical methods, analytical devices and biosensors
• Optical methods, analytical devices and biosensors
• Spectrophotometric methods, analytical devices and biosensors
• Chromatographic techniques
• Lateral flow devices for DNA/RNA analysis
• Sample preparation for nucleic acids analysis
• New nanomaterials as solid support or reporters for nucleic acids analysis
• Target or signal amplification-based biosensors
• Nucleic acids as biomarkers in diagnostics
• Nucleic acids analysis for food authentication purposes and species identification
The amount and the quality of the isolated genetic material is very crucial for the effective performance of nucleic acid-based methods. Moreover, new analytical methods are required that provide fast analysis with high detectability, sensitivity and specificity. In this context, innovative analytical devices and biosensors with enhanced analytical performance, along with potential portability and ease of use are in the forefront. New materials are also exploited as reporters to enhance the detectability of the methods and devices. Innovative protocols are developed for target recycling and/or signal enhancement to increase the detectability and the sensitivity of the methods. In addition, simple and cost-effective analytical devices and biosensors are needed to provide rapid analysis, without requiring qualified personnel for their performance.
We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:
• Analytical methods for nucleic acids analysis
• Novel target amplification and non-amplification techniques
• Analytical devices and biosensors for nucleic acids analysis
• Rapid methods, analytical devices and biosensors for nucleic acids analysis
• Electrochemical methods, analytical devices and biosensors
• Optical methods, analytical devices and biosensors
• Spectrophotometric methods, analytical devices and biosensors
• Chromatographic techniques
• Lateral flow devices for DNA/RNA analysis
• Sample preparation for nucleic acids analysis
• New nanomaterials as solid support or reporters for nucleic acids analysis
• Target or signal amplification-based biosensors
• Nucleic acids as biomarkers in diagnostics
• Nucleic acids analysis for food authentication purposes and species identification
Keywords: DNA, RNA, biosensors, nanomaterials, nanoparticles
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
