About this Research Topic
Bone infection, a kind of severe clinical infection, can arise from various sources, including contiguous spread from surrounding tissue, surgical procedures, or systemic bacteraemia. This complex condition encompasses implant-associated osteomyelitis, fracture-related infection, acute haematogenous osteomyelitis, diabetic foot infection, septic arthritis, and native spinal osteomyelitis. While the combination of antibacterial therapy and surgery remains the gold standard for treating bone infections, clinicians face challenges in managing bone-defect infections. Despite significant progress in curative treatment options, issues such as delayed bone union, nonunion, and joint stiffness persist.
In recent years, bone tissue engineering has emerged as a promising approach for addressing bone infection. By providing a temporary scaffold that supports the integration of new bone into defect areas and mimicking the natural bone extracellular matrix (ECM), tissue engineering creates a favorable microenvironment for cell adhesion, proliferation, and differentiation. This exciting field has attracted growing interest as a powerful strategy for preventing and treating bone infection.
This Research Topic aims to present the latest advancements in bone tissue engineering specifically targeting bone infection. We welcome comprehensive articles and reviews that explore the use of antibacterial implants, scaffolds, hydrogels, and bone cement, all of which should possess osteoinductive, osteogenic, or osseointegration properties. By promoting the development of effective antibacterial biomaterials, our ultimate goal is to reduce the occurrence, mortality, and morbidity associated with bone infection. We invite submissions on the following topics, but are not limited to:
- Tissue Engineering Strategies for Bone Infection
- Antibacterial Biomaterials for Bone Infection
- Antibacterial Hydrogels in Bone Tissue Engineering
- Scaffold Design and Antibacterial Properties
- Advancements in Antibacterial Implants
- Novel Antibacterial Bone Cement Types
In recent years, bone tissue engineering has emerged as a promising approach for addressing bone infection. By providing a temporary scaffold that supports the integration of new bone into defect areas and mimicking the natural bone extracellular matrix (ECM), tissue engineering creates a favorable microenvironment for cell adhesion, proliferation, and differentiation. This exciting field has attracted growing interest as a powerful strategy for preventing and treating bone infection.
This Research Topic aims to present the latest advancements in bone tissue engineering specifically targeting bone infection. We welcome comprehensive articles and reviews that explore the use of antibacterial implants, scaffolds, hydrogels, and bone cement, all of which should possess osteoinductive, osteogenic, or osseointegration properties. By promoting the development of effective antibacterial biomaterials, our ultimate goal is to reduce the occurrence, mortality, and morbidity associated with bone infection. We invite submissions on the following topics, but are not limited to:
- Tissue Engineering Strategies for Bone Infection
- Antibacterial Biomaterials for Bone Infection
- Antibacterial Hydrogels in Bone Tissue Engineering
- Scaffold Design and Antibacterial Properties
- Advancements in Antibacterial Implants
- Novel Antibacterial Bone Cement Types
Keywords: Bone infection, tissue engineering, antibacterial biomaterial, antibacterial implants, osteogenesis
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
