About this Research Topic
Biological tissues in our human body are immensely diverse, dynamic and heterogeneous. They are usually tightly regulated to maintain homeostasis but can be compromised due to disease, ageing and injuries. Throughout history, various biomaterials have been developed and adapted to interface with our biological systems to facilitate repairing tissues and management of disease progression.
From surgical sutures for routine wound closure to immunomodulating hydrogels for cancer treatment, biomaterials have demonstrated the potential of advanced biointerfaces to instruct and normalize tissues’ form and functions. However, the traditional “one-size-fits-all” biomaterial engineering strategy failed to consider individual complexity, including but not limited to age, sex, and ethnicity, which often leads to undesired treatment outcomes.
Therefore, novel biomaterial and biointerface designs and fabrication approaches are in great demand to emulate the complex pathophysiological features of biological tissues, which will ultimately inspire us to engineer instructive biomaterials to manage patients’ disease progression with high precision. Our evolving understanding of material science starts to allow us to design biomaterials which better mimic various mechanical, chemical and biological properties and functionalities of biological materials. The emergence of bioprinting has offered unprecedented
controllability of biomaterial architecture and bio interactions. These novel biomaterial design principles and biomanufacturing technologies hold great promise to elevate our understanding of human diversity and accelerate the optimization of precision medicine.
The current Research Topic calls for new insight and research progress on designing next-generation biomaterials and biointerfaces for precision medicine. We welcome the submission of original research, review, mini-review, and perspective. Examples of the themes include but are not limited to:
- Precision biomaterials and biointerface
- Biomimetic materials and interface
- Bioprinting personalized disease models
- Clinical translation of biomaterials
From surgical sutures for routine wound closure to immunomodulating hydrogels for cancer treatment, biomaterials have demonstrated the potential of advanced biointerfaces to instruct and normalize tissues’ form and functions. However, the traditional “one-size-fits-all” biomaterial engineering strategy failed to consider individual complexity, including but not limited to age, sex, and ethnicity, which often leads to undesired treatment outcomes.
Therefore, novel biomaterial and biointerface designs and fabrication approaches are in great demand to emulate the complex pathophysiological features of biological tissues, which will ultimately inspire us to engineer instructive biomaterials to manage patients’ disease progression with high precision. Our evolving understanding of material science starts to allow us to design biomaterials which better mimic various mechanical, chemical and biological properties and functionalities of biological materials. The emergence of bioprinting has offered unprecedented
controllability of biomaterial architecture and bio interactions. These novel biomaterial design principles and biomanufacturing technologies hold great promise to elevate our understanding of human diversity and accelerate the optimization of precision medicine.
The current Research Topic calls for new insight and research progress on designing next-generation biomaterials and biointerfaces for precision medicine. We welcome the submission of original research, review, mini-review, and perspective. Examples of the themes include but are not limited to:
- Precision biomaterials and biointerface
- Biomimetic materials and interface
- Bioprinting personalized disease models
- Clinical translation of biomaterials
Keywords: Biomaterial, biointerface, precision medicine, translation, microenvironment
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
