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Manuscript Submission Deadline 29 May 2024

Type 2 diabetes (T2D) is a worldwide health problem. It is increasingly common in adults, as well as it accounts for a significant proportion of youth-onset diabetes in at-risk populations. Obese children and adolescents with a family history of T2D and specific genetic backgrounds have the highest risk of developing T2D. Type T2D in youth is diagnosed based on plasma glucose criteria, either a fasting plasma glucose value above 126 mg/dL (7.0 mmol/L) or a 2-h plasma glucose value above 200 mg/dL (11.1 mmol/L) after a 75 g oral glucose load. Glycated hemoglobin above 6.5% (48 mmol/mol) is now considered a diagnostic criterion as well. T2D can be also diagnosed also in subjects with symptoms of hyperglycemia and random plasma glucose above 200 mg/dL
(11.1 mmol/L).

Over the last 2 decades, the papers about the clinical features and the epidemiology of T2D in youth have significantly increased. Ongoing research about treatment and pathophysiology is producing interesting results for researchers and for clinicians.

This Research Topic focuses on high-quality papers that address clinical and epidemiological issues of T2D in youth. Papers about Omics science or other kinds of molecular studies in this field are acknowledged. Contributions from a wide range of professions are welcome. Case reports, case series, original research papers, and state-of-the-art reviews will be accepted.

Keywords: Youth-Onset Type 2 Diabetes, obesity, clinical, epidemiology, omics, molecular study


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Type 2 diabetes (T2D) is a worldwide health problem. It is increasingly common in adults, as well as it accounts for a significant proportion of youth-onset diabetes in at-risk populations. Obese children and adolescents with a family history of T2D and specific genetic backgrounds have the highest risk of developing T2D. Type T2D in youth is diagnosed based on plasma glucose criteria, either a fasting plasma glucose value above 126 mg/dL (7.0 mmol/L) or a 2-h plasma glucose value above 200 mg/dL (11.1 mmol/L) after a 75 g oral glucose load. Glycated hemoglobin above 6.5% (48 mmol/mol) is now considered a diagnostic criterion as well. T2D can be also diagnosed also in subjects with symptoms of hyperglycemia and random plasma glucose above 200 mg/dL
(11.1 mmol/L).

Over the last 2 decades, the papers about the clinical features and the epidemiology of T2D in youth have significantly increased. Ongoing research about treatment and pathophysiology is producing interesting results for researchers and for clinicians.

This Research Topic focuses on high-quality papers that address clinical and epidemiological issues of T2D in youth. Papers about Omics science or other kinds of molecular studies in this field are acknowledged. Contributions from a wide range of professions are welcome. Case reports, case series, original research papers, and state-of-the-art reviews will be accepted.

Keywords: Youth-Onset Type 2 Diabetes, obesity, clinical, epidemiology, omics, molecular study


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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