About this Research Topic
Due to the global demand for quick and cheap analytical methods, the research on the design of a new generation of miniature diagnostic devices like (bio)sensors has become prominent. Every biosensor is composed of two intimately associated elements: a receptor layer and a transducer. The receptor layer is built of biorecognition material, which recognizes the desired analyte, whereas the transducer converts the (bio)chemical signal resulting from the interaction of the analyte with the receptor into a digital electronic signal. Nowadays, there is observed increased interest in nanomaterial-based sensing devices, due to unusual properties of wide range of nanomaterials. Very often such (bio)sensors are fabricated in the form of micro-total analysis system (µTAS) or lab-on-chip (LOC). Thus, an in-depth understanding of physical, biological, and digital cues is highly relevant to the performance and development of nanomaterial-based sensor or biosensor devices.
The goal of this Research Topic is to design new (bio)sensor-based systems based on nanomaterials for relevant molecule detection, which could contribute to the intensification of work in the investigation of a new generation of miniature analytical devices with wide range of application possibilities. In addition, the investigation of interaction mechanisms of protein-modified electrode is an essential step during modelling of biosensors. Nanomaterials, which are intended for electrode modification and chosen of a suitable immobilization method have to maintain protein structure and their function in order to retain their biological activity after immobilization and to remain tightly bound to the surface. Due to this, the important additional aim is the measurement of the catalytic activity of the immobilized proteins and the chemical modification of electrodes to provide efficient methods for immobilization.
For designing a biosensor the most important part is to create a chemically and biologically modified platform (like an electrode). It can be defined as an electrode made of material (i.e. nanomaterial), which coats the electrode surface. Application in the receptor part layer of a nanomaterial allows improving the parameters of a biosensor, like a sensor sensitivity, increasing the limit of detection and lengthening the life of the sensor. Nanomaterials also provide a place for anchoring the protein with maintaining its catalytic activity. We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:
• Novel nanomaterials for sensor applications which may include novel design, synthetic pathways, surface modification, and well as structural characterisation
• Creative design of nanomaterial-based sensing devices
• Novel detection platforms based on innovative nanomaterials
The goal of this Research Topic is to design new (bio)sensor-based systems based on nanomaterials for relevant molecule detection, which could contribute to the intensification of work in the investigation of a new generation of miniature analytical devices with wide range of application possibilities. In addition, the investigation of interaction mechanisms of protein-modified electrode is an essential step during modelling of biosensors. Nanomaterials, which are intended for electrode modification and chosen of a suitable immobilization method have to maintain protein structure and their function in order to retain their biological activity after immobilization and to remain tightly bound to the surface. Due to this, the important additional aim is the measurement of the catalytic activity of the immobilized proteins and the chemical modification of electrodes to provide efficient methods for immobilization.
For designing a biosensor the most important part is to create a chemically and biologically modified platform (like an electrode). It can be defined as an electrode made of material (i.e. nanomaterial), which coats the electrode surface. Application in the receptor part layer of a nanomaterial allows improving the parameters of a biosensor, like a sensor sensitivity, increasing the limit of detection and lengthening the life of the sensor. Nanomaterials also provide a place for anchoring the protein with maintaining its catalytic activity. We welcome Original Research, Review, Mini Review and Perspective articles on themes including, but not limited to:
• Novel nanomaterials for sensor applications which may include novel design, synthetic pathways, surface modification, and well as structural characterisation
• Creative design of nanomaterial-based sensing devices
• Novel detection platforms based on innovative nanomaterials
Keywords: Nanomaterials, Surface modification, Biosensors, Electrochemistry, Optical sensors
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
