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About this Research Topic

Manuscript Submission Deadline 24 January 2024
Manuscript Extension Submission Deadline 23 February 2024

Valvular heart disease (VHD) is a rapidly increasing cause of global cardiovascular morbidity and mortality. Ventricular remodeling plays a crucial role in determining prognosis and outcomes in VHD. There is a growing interest in studying the underlying biomolecular pathways of ventricular remodeling. Multimodality imaging plays a particularly important role in determining the onset of pathologic ventricular remodeling and optimal timing for surgery. Given the significant interest in this field and the numerous unanswered clinical and basic/translational questions, this research topic aims to provide an overview of the latest advances in our understanding of the mechanisms of ventricular remodeling, its association with clinical outcomes, and regression post valve intervention.

The topic covers various aspects of ventricular remodeling in VHD including but not limited to the following:
● Molecular and cellular mechanisms underlying ventricular remodeling in VHD
● Evaluation of ventricular remodeling using multimodality imaging techniques
● Role of ventricular remodeling in predicting prognosis, outcomes, and timing of surgery
● Impact of valve surgery on ventricular remodeling and regression
● Translational research bridging basic science and clinical practice in ventricular remodeling

Frontiers in Cardiovascular Medicine invites researchers and experts in the field to submit their research focused on mechanisms, diagnostic evaluation, clinical implications, and therapeutic approaches related to ventricular remodeling in valvular heart disease. The journal welcomes various article types, including case reports, case series, cohort studies, reviews, meta-analyses, opinion pieces, as well as basic and translational research.

Keywords: Ventricular Remodeling


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Valvular heart disease (VHD) is a rapidly increasing cause of global cardiovascular morbidity and mortality. Ventricular remodeling plays a crucial role in determining prognosis and outcomes in VHD. There is a growing interest in studying the underlying biomolecular pathways of ventricular remodeling. Multimodality imaging plays a particularly important role in determining the onset of pathologic ventricular remodeling and optimal timing for surgery. Given the significant interest in this field and the numerous unanswered clinical and basic/translational questions, this research topic aims to provide an overview of the latest advances in our understanding of the mechanisms of ventricular remodeling, its association with clinical outcomes, and regression post valve intervention.

The topic covers various aspects of ventricular remodeling in VHD including but not limited to the following:
● Molecular and cellular mechanisms underlying ventricular remodeling in VHD
● Evaluation of ventricular remodeling using multimodality imaging techniques
● Role of ventricular remodeling in predicting prognosis, outcomes, and timing of surgery
● Impact of valve surgery on ventricular remodeling and regression
● Translational research bridging basic science and clinical practice in ventricular remodeling

Frontiers in Cardiovascular Medicine invites researchers and experts in the field to submit their research focused on mechanisms, diagnostic evaluation, clinical implications, and therapeutic approaches related to ventricular remodeling in valvular heart disease. The journal welcomes various article types, including case reports, case series, cohort studies, reviews, meta-analyses, opinion pieces, as well as basic and translational research.

Keywords: Ventricular Remodeling


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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