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Advanced immunization technologies, including adjuvants, vectors and prime-boost combinations, have the potential to make an enormous contribution in the development of next generation vaccines. New technologies and big data analysis, including genomics and systems biology, are fueling advances in our ...

Advanced immunization technologies, including adjuvants, vectors and prime-boost combinations, have the potential to make an enormous contribution in the development of next generation vaccines. New technologies and big data analysis, including genomics and systems biology, are fueling advances in our understanding of human immunology, transforming the old field of vaccinology and shaping the future of medicine.

The High Impact Project ADITEC (Advanced Immunization Technologies, www.aditecproject.eu) funded through the 7th Framework Programme for Research and Innovation of the European Union, has catalyzed scientists from 42 institutions in 13 European countries and USA. ADITEC has made significant advances in the development of novel immunization technologies, adjuvants, vectors and delivery systems, formulations and vaccination methods optimized for different age groups. The project has successfully conducted 12 clinical trials studied through a systems biology approach. Through the ADITEC’s continual success and achievement, 220 scientific publications in international peer-reviewed journals have been produced to date.

The aim of this Research Topic is to assemble a series of reviews and original research articles, which highlight the advances made by the ADITEC project in the development of advanced immunization technologies and in the study of human vaccine immune responses through the latest generation methodologies.

Keywords: ADITEC, Immunization Technologies, Adjuvants, Vaccine Vectors, Systems vaccinology, Human Immonology


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