About this Research Topic
Endometriosis is defined as the presence of endometrial-like endometrial cells, glands and stroma outside the uterus, causing a strong inflammatory-like microenvironment in the affected tissue. The exact prevalence of endometriosis is unknown, but the estimates range from 2–10 % of women of reproductive age, to 50 % of infertile women. Its etiopathogenesis of endometriosis still remains controversial: immune, hormonal, genetic, and epigenetic factors may be all involved, and several theories have been proposed to explain it.
Endometriosis can cause several symptoms and signs, including acute and chronic pelvic pain, dysmenorrhea, dyspareunia, abnormal vaginal bleeding, infertility/sterility and, in the severe stage, gastrointestinal and urological symptoms. Three main clinical presentations have been described: peritoneal endometriosis, endometriotic ovarian cysts (i.e., endometriomas), and deeply infiltrating endometriosis (DIE) .The latter is considered the most aggressive presentation of endometriosis, penetrating more than 5mm in affected tissues and affecting approximately 20% of all women with the disease. These infiltrating lesions respond as other implants to various hormonal therapies, but it is not a definitive management for symptomatic patients, for which a surgical treatment may be required. Multiple minimally invasive surgical approaches and techniques are available for treatment of endometriosis and often require the expertise of both gynecologist and general surgeon or urologist. The purpose of endometriosis surgery is to obtain good long-term outcomes regarding pain relief, recurrence rates, and fertility without compromising the function of involved organs.
Considering that minimally invasive approaches, including laparoscopy and robotic surgery, have gained the role of gold standard management for the surgical treatment of endometriosis, the aim of this Research Topic will be to offer a clear, high-quality and evidence-based overview.
In this Research Topic we welcome Original Research, Methods, Review, Mini Review, Perspective, Case Report, General Commentary, Opinion and Clinical Study Protocol that help in the understanding of and the discussion on the above mentioned surgical approaches for endometriosis.
Image: Hope, 2014, acrylic on canvas.
Jodie Dunne BHSc, GDipPsych, GDipSexol, MHRM, MCouns (current candidate) M: +61 414577739.
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