About this Research Topic
This Research Topics aims to showcase the latest advances and applications of zebrafish models in cancer research, covering various aspects from molecular mechanisms to drug discovery. We will publish research findings, methodologies, and reviews on cancer research using zebrafish, offering various perspectives inspired by new insights.
In recent years, there has been an increase in cancer research initiatives utilizing zebrafish. Not only are zebrafish being used for the exploration of new anticancer drugs in carcinogenesis and cancer transplantation models, but they are also employed to elucidate the impact of elements such as immune and stromal cells within the tumor microenvironment on tumor growth and metastasis. Research has been conducted on specific genes and signaling pathways common to vertebrates, and the effectiveness of new treatments targeting the tumor microenvironment based on this model is also being examined. These promising results encourage the further exploration and application of zebrafish models for cancer discovery and drug development.
We accept all areas of cancer research using zebrafish. However, we give preference to studies that aim to clarify host-cancer interactions in zebrafish, including the tumor microenvironment, tumor angiogenesis, distant metastasis, and immune responses. We primarily accept research articles and review articles. For research results that are impactful yet immature, we also accept brief reports. Additionally, we welcome articles introducing new cancer-zebrafish technologies, commonly known as methodology articles.
In recent years, there has been an increase in cancer research initiatives utilizing zebrafish. Not only are zebrafish being used for the exploration of new anticancer drugs in carcinogenesis and cancer transplantation models, but they are also employed to elucidate the impact of elements such as immune and stromal cells within the tumor microenvironment on tumor growth and metastasis. Research has been conducted on specific genes and signaling pathways common to vertebrates, and the effectiveness of new treatments targeting the tumor microenvironment based on this model is also being examined. These promising results encourage the further exploration and application of zebrafish models for cancer discovery and drug development.
We accept all areas of cancer research using zebrafish. However, we give preference to studies that aim to clarify host-cancer interactions in zebrafish, including the tumor microenvironment, tumor angiogenesis, distant metastasis, and immune responses. We primarily accept research articles and review articles. For research results that are impactful yet immature, we also accept brief reports. Additionally, we welcome articles introducing new cancer-zebrafish technologies, commonly known as methodology articles.
Keywords: Xenograft, Xenotransplantation, Omics, Next generation sequencing, Transgenic, Knockout, Screening, Phenotype
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
