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Manuscript Submission Deadline 10 May 2024

A new classification of chronic pain has been implemented in the 11th revision of the International Classification of Diseases. (ICD-11). Its inclusion was motivated by the hope that the systematic and substantially improved classification would act as a catalyst for research into chronic pain and help to define better treatment pathways for patients with different types of chronic pain and eventually also improve treatment options. The classification differentiates between chronic primary pain and chronic secondary pain. All diagnoses of chronic pain, irrespective of the differential diagnosis, are conceptualized as multifactorial with biological, psychological, and social factors contributing to individual extents. In addition, optional specifiers in the ICD-11 allow a dimensional characterization of pain severity, which is not only seen as a function of pain intensity, but also pain-related distress and pain-related interference. This will allow future studies to better characterize chronic pain, which will eventually increase our understanding of the diagnosis and its treatment.

The goal of this Research Topic is to bring together a collection of articles that highlight the chances and hurdles of using the new ICD-11 chronic pain classification in basic as well as clinical pain research (e.g., diagnosis and treatment of patients) and in clinical care with regard to all age groups. By doing so, the scientific foundation of the new classification will be strengthened. This, in turn, can contribute to improved implementation of the new classification and advocate its use and fertility for research.

We welcome the submission of manuscripts related to the new ICD-11 chronic pain diagnoses . We particularly invite papers that contribute data showing if and how the new diagnoses were utilized in different contexts. This includes (but is not limited to):
• Epidemiology of chronic pain (chronic primary pain and chronic secondary pain or any of its more specific sub-categories)
• Different populations and age groups (e.g., children, adolescents, adults, older people)
• Application of the classification in different settings (e.g., primary care, different specialty settings, low- and middle-income countries)
• Use of the classification for diagnosis
• Treatment planning and prognosis
• Prediction (e.g., pain course, treatment response)
• Basic research (e.g., pain mechanisms in chronic primary and chronic secondary pain)
• Qualitative examinations
• Meta-analytic approaches and systematic reviews
• Use of the new chronic pain specifier that extends to pain-related distress and functioning in addition to pain intensity

Keywords: chronic pain, chronic primary pain, chronic secondary pain, ICD-11, distress, interference, functional disability, treatment, diagnosis, prediction, prognosis, innovation, mechanisms, experimental, basic science, epidemiology, children, adults


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

A new classification of chronic pain has been implemented in the 11th revision of the International Classification of Diseases. (ICD-11). Its inclusion was motivated by the hope that the systematic and substantially improved classification would act as a catalyst for research into chronic pain and help to define better treatment pathways for patients with different types of chronic pain and eventually also improve treatment options. The classification differentiates between chronic primary pain and chronic secondary pain. All diagnoses of chronic pain, irrespective of the differential diagnosis, are conceptualized as multifactorial with biological, psychological, and social factors contributing to individual extents. In addition, optional specifiers in the ICD-11 allow a dimensional characterization of pain severity, which is not only seen as a function of pain intensity, but also pain-related distress and pain-related interference. This will allow future studies to better characterize chronic pain, which will eventually increase our understanding of the diagnosis and its treatment.

The goal of this Research Topic is to bring together a collection of articles that highlight the chances and hurdles of using the new ICD-11 chronic pain classification in basic as well as clinical pain research (e.g., diagnosis and treatment of patients) and in clinical care with regard to all age groups. By doing so, the scientific foundation of the new classification will be strengthened. This, in turn, can contribute to improved implementation of the new classification and advocate its use and fertility for research.

We welcome the submission of manuscripts related to the new ICD-11 chronic pain diagnoses . We particularly invite papers that contribute data showing if and how the new diagnoses were utilized in different contexts. This includes (but is not limited to):
• Epidemiology of chronic pain (chronic primary pain and chronic secondary pain or any of its more specific sub-categories)
• Different populations and age groups (e.g., children, adolescents, adults, older people)
• Application of the classification in different settings (e.g., primary care, different specialty settings, low- and middle-income countries)
• Use of the classification for diagnosis
• Treatment planning and prognosis
• Prediction (e.g., pain course, treatment response)
• Basic research (e.g., pain mechanisms in chronic primary and chronic secondary pain)
• Qualitative examinations
• Meta-analytic approaches and systematic reviews
• Use of the new chronic pain specifier that extends to pain-related distress and functioning in addition to pain intensity

Keywords: chronic pain, chronic primary pain, chronic secondary pain, ICD-11, distress, interference, functional disability, treatment, diagnosis, prediction, prognosis, innovation, mechanisms, experimental, basic science, epidemiology, children, adults


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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