About this Research Topic
Infection may be a primary cause of renal disease (e.g. postinfectious glomerulonephritis) or affect the kidneys on a background of debilitating illnesses and previous medical interventions. Renal disease may arise as a consequence of immune responses to a pathogen, direct invasion by the microorganism, or the effects of infection on the systemic or local circulations. Infectious nephropathies may range from mild proteinuria to severe kidney damage, i.e. acute kidney injury (AKI). Recent advancements in the field of nephrology indicate that both mild and severe degrees of AKI may lead to the development of Chronic Kidney Disease (CKD). In addition, existing literature shows unsatisfactory outcomes of patients after infection-induced nephropathies, especially after AKI. Nephropathies associated with the infectious diseases are usually neglected in general clinical practice and much more attention is paid to the patient's recovery from underlying infection. A growing body of evidence has suggested that infection-induced nephropathies are associated with high disease burden in terms of increased mortality and prolonged hospitalization, which is of particular concern among countries facing rapid surge of infectious diseases. This area is needed to be fully explored by evaluating the impact of infectious disease on kidney functions and renal outcomes.
Keywords: Infection, Infectious Diseases, Nephropathies, Acute Kidney Injury, Chronic Kidney Disease
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