Background: The microbiome-gut-brain axis has gained significant attention in recent years as a potential key player in regulating mental health. It consists of bidirectional communication between the gut microbiota and the central nervous system, influencing various aspects of brain function and behavior. Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder characterized by the persistence of distressing symptoms following a traumatic event. Emerging evidence suggests that disruptions in the microbiome-gut-brain axis may contribute to the pathophysiology of PTSD as well as the persistence of PTSD symptoms. Understanding the underlying mechanisms and exploring potential therapeutic interventions hold great promise in improving the lives of individuals affected by PTSD.
Goal: The goal of this Research Topic is to shed light on the intricate relationship between the microbiome-gut-brain axis and posttraumatic stress disorder. We aim to address the existing knowledge gaps, identify mechanisms of microbiome-gut-brain axis signaling, and explore potential therapeutic strategies targeting the microbiome for the prevention and treatment of PTSD. By bringing together multidisciplinary research, we strive to enhance our understanding of the complex neurobiology underlying PTSD and pave the way for innovative interventions.
3. Scope and Information for Authors: This Research Topic welcomes contributions from researchers and clinicians working in the fields of microbiology, neuroscience, psychiatry, and related disciplines. We encourage both clinical and preclinical research including original research articles, review papers, and opinion pieces that focus on, but are not limited to, the following themes:
• The role of gut microbiota in posttraumatic stress disorder and PTSD-related symptoms (e.g., anxiety, depression, insomnia)
• Microbiome-gut-brain axis signaling in PTSD vulnerability , pathophysiology, or persistence of PTSD symptoms
• Influence of stress and trauma on gut microbial composition and function
• Studies investigating therapeutic interventions targeting the microbiome (prebiotics, probiotics, psychobiotics, synbiotics, diet) in preventing or ameliorating PTSD symptoms
• Understanding the impact of microbiota-mediated interventions on microbiome-gut-brain axis signaling and stress resilience
By collating diverse research, we aim to facilitate a comprehensive understanding of the microbiome-gut-brain axis in the context of posttraumatic stress disorder, and inspire innovative approaches to prevention, diagnosis, and treatment.
Background: The microbiome-gut-brain axis has gained significant attention in recent years as a potential key player in regulating mental health. It consists of bidirectional communication between the gut microbiota and the central nervous system, influencing various aspects of brain function and behavior. Posttraumatic stress disorder (PTSD) is a complex psychiatric disorder characterized by the persistence of distressing symptoms following a traumatic event. Emerging evidence suggests that disruptions in the microbiome-gut-brain axis may contribute to the pathophysiology of PTSD as well as the persistence of PTSD symptoms. Understanding the underlying mechanisms and exploring potential therapeutic interventions hold great promise in improving the lives of individuals affected by PTSD.
Goal: The goal of this Research Topic is to shed light on the intricate relationship between the microbiome-gut-brain axis and posttraumatic stress disorder. We aim to address the existing knowledge gaps, identify mechanisms of microbiome-gut-brain axis signaling, and explore potential therapeutic strategies targeting the microbiome for the prevention and treatment of PTSD. By bringing together multidisciplinary research, we strive to enhance our understanding of the complex neurobiology underlying PTSD and pave the way for innovative interventions.
3. Scope and Information for Authors: This Research Topic welcomes contributions from researchers and clinicians working in the fields of microbiology, neuroscience, psychiatry, and related disciplines. We encourage both clinical and preclinical research including original research articles, review papers, and opinion pieces that focus on, but are not limited to, the following themes:
• The role of gut microbiota in posttraumatic stress disorder and PTSD-related symptoms (e.g., anxiety, depression, insomnia)
• Microbiome-gut-brain axis signaling in PTSD vulnerability , pathophysiology, or persistence of PTSD symptoms
• Influence of stress and trauma on gut microbial composition and function
• Studies investigating therapeutic interventions targeting the microbiome (prebiotics, probiotics, psychobiotics, synbiotics, diet) in preventing or ameliorating PTSD symptoms
• Understanding the impact of microbiota-mediated interventions on microbiome-gut-brain axis signaling and stress resilience
By collating diverse research, we aim to facilitate a comprehensive understanding of the microbiome-gut-brain axis in the context of posttraumatic stress disorder, and inspire innovative approaches to prevention, diagnosis, and treatment.