Research Topic

Bioactive Compounds and Cardiovascular Health

About this Research Topic

Diet is often considered one of the most “modifiable” risk factors in cardiovascular (CV) disease prevention and it is now frequently used as prevention approach. However, a nutritional role for food is not sufficient anymore, and it is now supposed to provide extra health benefits or reduce occasional illness, opening up a role for nutraceuticals. The NIH Office of Dietary Supplements has defined dietary bioactives as “compounds that are constituents in foods and dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status”. Bioactives vary widely in chemical structure and function, and the type and concentration of bioactive vary widely in different foods. Research is ongoing and further information regarding the ability of nutrients and food bioactive compounds to modulate eventual progression of cardiovascular disease is needed.

In this Research Topic we aim to attract the latest research on bioactives consumption and cardiovascular health. This Topic may provide novel therapeutic approaches for intervention that will be certainly of significant interest to many clinical investigators and basic researchers.

All types of human studies will be considered—short-term and long-term intervention trials and epidemiological studies that focus on a variety of CV diseases and risk factors.

In addition, the submission of studies investigating mechanistic actions, modelling approaches, proteins, food intake, genetic factors, metabolism, microbiome, novel sources and other emerging research areas are strongly encouraged.


Keywords: Bioactive food compounds, cardiovascular diseases, dietary interventions, mechanisms of action, CV prevention


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Diet is often considered one of the most “modifiable” risk factors in cardiovascular (CV) disease prevention and it is now frequently used as prevention approach. However, a nutritional role for food is not sufficient anymore, and it is now supposed to provide extra health benefits or reduce occasional illness, opening up a role for nutraceuticals. The NIH Office of Dietary Supplements has defined dietary bioactives as “compounds that are constituents in foods and dietary supplements, other than those needed to meet basic human nutritional needs, which are responsible for changes in health status”. Bioactives vary widely in chemical structure and function, and the type and concentration of bioactive vary widely in different foods. Research is ongoing and further information regarding the ability of nutrients and food bioactive compounds to modulate eventual progression of cardiovascular disease is needed.

In this Research Topic we aim to attract the latest research on bioactives consumption and cardiovascular health. This Topic may provide novel therapeutic approaches for intervention that will be certainly of significant interest to many clinical investigators and basic researchers.

All types of human studies will be considered—short-term and long-term intervention trials and epidemiological studies that focus on a variety of CV diseases and risk factors.

In addition, the submission of studies investigating mechanistic actions, modelling approaches, proteins, food intake, genetic factors, metabolism, microbiome, novel sources and other emerging research areas are strongly encouraged.


Keywords: Bioactive food compounds, cardiovascular diseases, dietary interventions, mechanisms of action, CV prevention


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

31 December 2017 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

31 December 2017 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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