Research Topic

Solid State Fermentation (SSF): Advancements and Challenges

About this Research Topic

The advent of biotechnology in the 20th century had a tremendous impact on human society. The possibility of mass-producing a wide range of antibiotics, chemicals and complex proteins, previously at best only available in small quantity, greatly contributed to human health and well-being. Instrumental to such development, industrial fermentation played a key role in realizing the full potential of genetic engineering, microbial characterization and enzyme technology; matching engineering to biology, and showing the intimate continuity between these subjects, real-life improvements became possible.

Next to submerged cultivation, where all biologic and thermodynamic reactions take place in a liquid medium, a number of processes are still performed on the surface of substrate or matrixes, and are generally referred to as solid state fermentation (SSF). Although the field of application can vary, from traditional small-scale food processes to industrial scale bioconversion, the general challenges involving such processes tend to be invariably the same: analytical, thermodynamic and even practical hurdles, often requiring creative thinking and cutting-edge technology to be overcome.

This Research Topic aims to collect original manuscripts on recent development of technology, analytical methods, cultivation system and microbe engineering involved in solid state fermentation, with particular attention to automation and industrial or large-scale bioprocessing. Potential topics include, but are not limited to, recent developments on biomass-to-chemical compounds, applications in food biotechnology or food processing, novel cultivation systems for biopharmaceutical applications or miniaturized solid state bioreactors.


Keywords: Solid state fermentation, bioprocessing, food technology, process control, bioreactor


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

The advent of biotechnology in the 20th century had a tremendous impact on human society. The possibility of mass-producing a wide range of antibiotics, chemicals and complex proteins, previously at best only available in small quantity, greatly contributed to human health and well-being. Instrumental to such development, industrial fermentation played a key role in realizing the full potential of genetic engineering, microbial characterization and enzyme technology; matching engineering to biology, and showing the intimate continuity between these subjects, real-life improvements became possible.

Next to submerged cultivation, where all biologic and thermodynamic reactions take place in a liquid medium, a number of processes are still performed on the surface of substrate or matrixes, and are generally referred to as solid state fermentation (SSF). Although the field of application can vary, from traditional small-scale food processes to industrial scale bioconversion, the general challenges involving such processes tend to be invariably the same: analytical, thermodynamic and even practical hurdles, often requiring creative thinking and cutting-edge technology to be overcome.

This Research Topic aims to collect original manuscripts on recent development of technology, analytical methods, cultivation system and microbe engineering involved in solid state fermentation, with particular attention to automation and industrial or large-scale bioprocessing. Potential topics include, but are not limited to, recent developments on biomass-to-chemical compounds, applications in food biotechnology or food processing, novel cultivation systems for biopharmaceutical applications or miniaturized solid state bioreactors.


Keywords: Solid state fermentation, bioprocessing, food technology, process control, bioreactor


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

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Submission Deadlines

28 February 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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Topic Editors

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Submission Deadlines

28 February 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

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