Microbiomes exhibit an astounding genetic, physiological, and biochemical diversity, enabling their survival across diverse environmental conditions and in various hosts worldwide. With advances in sequencing technologies, our understanding of microbiomes' abilities and their effects on hosts and environments has significantly expanded. Researchers are now harnessing the expansive capabilities of microbes for bioremediation and various applications in biotechnology, agriculture, and medicine. By constructing synthetic microbial communities—novel in composition, genetics, and phenotypes—scientists can tackle foundational biological issues and address broader societal challenges. Nonetheless, expansive research is essential to thoroughly explore the significance and applications of synthetic microbiomes.This Research Topic aims to collect state-of-the-art knowledge regarding the manipulation of synthetic microbiomes, particularly focusing on animal gut microbiota. The gut microbiome is pivotal in nutrient metabolism, immune response, and the overall well-being of animals. Defined as engineered collections of microbes with unique or intentionally modified characteristics, synthetic microbiomes allow researchers to investigate how these communities can enhance nutrient absorption, prevent metabolic diseases, and boost animal health by influencing digestion and metabolism processes. Key to this research is also the understanding of interactions between synthetic and natural microbiota components.To further delve into this, the scope of this Research Topic covers various aspects pertaining to the influence of synthetic microbiomes on gut microbiota and subsequent host health outcomes. We encourage submissions exploring a range of topics including but not limited to:• Design and assembly of synthetic microbiomes• Mechanistic insights into synthetic microbiome interactions with gut microbiomes• The broad applications of synthetic microbiomes in animal nutrition and metabolism• Original research, reviews, and short communications that shed light on the functional dynamics and challenges of utilizing synthetic microbiomes in animal health scenarios are particularly welcome• Contributions are also solicited on studies identifying the functions of individual microbes.
Microbiomes exhibit an astounding genetic, physiological, and biochemical diversity, enabling their survival across diverse environmental conditions and in various hosts worldwide. With advances in sequencing technologies, our understanding of microbiomes' abilities and their effects on hosts and environments has significantly expanded. Researchers are now harnessing the expansive capabilities of microbes for bioremediation and various applications in biotechnology, agriculture, and medicine. By constructing synthetic microbial communities—novel in composition, genetics, and phenotypes—scientists can tackle foundational biological issues and address broader societal challenges. Nonetheless, expansive research is essential to thoroughly explore the significance and applications of synthetic microbiomes.This Research Topic aims to collect state-of-the-art knowledge regarding the manipulation of synthetic microbiomes, particularly focusing on animal gut microbiota. The gut microbiome is pivotal in nutrient metabolism, immune response, and the overall well-being of animals. Defined as engineered collections of microbes with unique or intentionally modified characteristics, synthetic microbiomes allow researchers to investigate how these communities can enhance nutrient absorption, prevent metabolic diseases, and boost animal health by influencing digestion and metabolism processes. Key to this research is also the understanding of interactions between synthetic and natural microbiota components.To further delve into this, the scope of this Research Topic covers various aspects pertaining to the influence of synthetic microbiomes on gut microbiota and subsequent host health outcomes. We encourage submissions exploring a range of topics including but not limited to:• Design and assembly of synthetic microbiomes• Mechanistic insights into synthetic microbiome interactions with gut microbiomes• The broad applications of synthetic microbiomes in animal nutrition and metabolism• Original research, reviews, and short communications that shed light on the functional dynamics and challenges of utilizing synthetic microbiomes in animal health scenarios are particularly welcome• Contributions are also solicited on studies identifying the functions of individual microbes.