About this Research Topic
With the development of high-throughput sequencing technology and multi-omics analysis methods, the study of the human microbiome has been deepening. Microbes play an important role in maintaining human health and the development of many diseases, especially in the fields of tumour biology and tumour immunology. Studies have shown that the microbial community influences immune escape, inflammatory response and metabolic regulation in the tumour microenvironment through multiple pathways, and plays a crucial role in tumourigenesis, development and treatment. Therefore, an in-depth study of the interaction between microbes and the tumour immune system is of great significance in revealing tumour mechanisms and developing novel therapeutic strategies.
This Research Topic seeks to gather and present the latest research findings on the immune interactions between microbes and tumors. We welcome original research papers, review articles, and perspective papers, particularly those that reveal the multi-faceted mechanisms by which microbes influence tumor immune responses. Suggested subthemes include:
--The role of microbial communities in tumorigenesis
--Microbial metabolites and the tumor immune microenvironment
--Microbially regulated tumor immune mechanisms
--Microbially regulated mechanisms of tumor drug resistance
Please note that manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by robust and relevant validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this Research Topic.
This Research Topic seeks to gather and present the latest research findings on the immune interactions between microbes and tumors. We welcome original research papers, review articles, and perspective papers, particularly those that reveal the multi-faceted mechanisms by which microbes influence tumor immune responses. Suggested subthemes include:
--The role of microbial communities in tumorigenesis
--Microbial metabolites and the tumor immune microenvironment
--Microbially regulated tumor immune mechanisms
--Microbially regulated mechanisms of tumor drug resistance
Please note that manuscripts consisting solely of bioinformatics or computational analysis of public genomic or transcriptomic databases which are not accompanied by robust and relevant validation (clinical cohort or biological validation in vitro or in vivo) are out of scope for this Research Topic.
Keywords: Microbes, Tumour Immunity, tumour progression, Host-microbe interactions, Microbial markers, tumourigenesis, tumour immune microenvironment, TME, Microbial metabolites
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.
