Allergic diseases represent a group of immune mediated disorders mainly attributed but not limited to IgE, Th2 cytokines and certain cell subsets. Breakthroughs in identifying new biomarkers, novel methodologies or its application for diagnosis and prognosis in the field of allergy have taken place in recent years. Therefore, it is primordial to introduce and spread these advancements and developments to clinical practitioners and researchers.Allergy diagnostic relies on different laboratory tests to give an input regarding specificity, severity, and disease prognosis, but also is used for immunotherapy follow up, complicated cases where skin prick or intradermal test turns negative or in allergic diseases where IgE is not involved. Regardless, different novel laboratory methodologies and biomarkers are in development for specific diseases of the allergic spectrum.Suitable themes for this topic include manuscripts regarding novel or developing laboratory methods and biomarkers related with the field of allergy in vitro, in animal models or in humans:• Classical Biomarkers in Allergy: tIgE, sIgE, eosinophils, classical tests with new approaches in allergy diagnostic.• Cellular Biomarkers in Allergy: Cell subsets such as, Th subsets, dendritic cells subsets, macrophages subsets, ILCs, B cell subsets, among others, that suggests participation or utility as potential biomarkers in allergy.• Soluble Biomarkers: Serum, tear, bronchoalveolar fluid, saliva, nasal secretions, Cytokines, soluble costimulatory molecules, among others, with involvement in allergy.• Novel and developing methodologies for Allergy diagnostic: Standardization or comparison of novel methods, techniques, singleplex vs multiplex platforms, and others used in allergy diagnostic.• Genetic biomarkers: Transcription factors, RNAs, polymorphisms, and others suggesting its participation in the pathophysiology or promising as biomarkers for allergic diseases.• Molecular Allergy: Comparison between Molecular Allergy and classical component/extract tests, applications of Molecular Allergy in diagnosis and immunotherapy selection, and patient clinical improvement monitoring.• Non-Immune biomarkers in allergy: Hormones, neurotransmitters, non-organic compounds, lipids, and others.All article types accepted by Frontiers are encouraged.
Allergic diseases represent a group of immune mediated disorders mainly attributed but not limited to IgE, Th2 cytokines and certain cell subsets. Breakthroughs in identifying new biomarkers, novel methodologies or its application for diagnosis and prognosis in the field of allergy have taken place in recent years. Therefore, it is primordial to introduce and spread these advancements and developments to clinical practitioners and researchers.Allergy diagnostic relies on different laboratory tests to give an input regarding specificity, severity, and disease prognosis, but also is used for immunotherapy follow up, complicated cases where skin prick or intradermal test turns negative or in allergic diseases where IgE is not involved. Regardless, different novel laboratory methodologies and biomarkers are in development for specific diseases of the allergic spectrum.Suitable themes for this topic include manuscripts regarding novel or developing laboratory methods and biomarkers related with the field of allergy in vitro, in animal models or in humans:• Classical Biomarkers in Allergy: tIgE, sIgE, eosinophils, classical tests with new approaches in allergy diagnostic.• Cellular Biomarkers in Allergy: Cell subsets such as, Th subsets, dendritic cells subsets, macrophages subsets, ILCs, B cell subsets, among others, that suggests participation or utility as potential biomarkers in allergy.• Soluble Biomarkers: Serum, tear, bronchoalveolar fluid, saliva, nasal secretions, Cytokines, soluble costimulatory molecules, among others, with involvement in allergy.• Novel and developing methodologies for Allergy diagnostic: Standardization or comparison of novel methods, techniques, singleplex vs multiplex platforms, and others used in allergy diagnostic.• Genetic biomarkers: Transcription factors, RNAs, polymorphisms, and others suggesting its participation in the pathophysiology or promising as biomarkers for allergic diseases.• Molecular Allergy: Comparison between Molecular Allergy and classical component/extract tests, applications of Molecular Allergy in diagnosis and immunotherapy selection, and patient clinical improvement monitoring.• Non-Immune biomarkers in allergy: Hormones, neurotransmitters, non-organic compounds, lipids, and others.All article types accepted by Frontiers are encouraged.