Nanopharmacology integrates nanotechnology to revolutionize therapeutic and diagnostic applications, employing natural-based nanoformulations like alginate, chitosan, and hyaluronic acid among others. These formulations are gaining attention due to their potential to enhance drug delivery efficacy while reducing toxicity. The properties of these nanocarriers, such as biodegradability, biocompatibility, and cytocompatibility, position them as promising candidates in the development of advanced drug delivery systems and diagnostic tools. However, challenges such as optimizing pharmacological efficacy, ensuring biopharmaceutical stability, and addressing biosafety and environmental impacts are critical hurdles that impede their clinical translation.
This Research Topic aims to explore cutting-edge approaches that address the pharmacological, biopharmaceutical, and safety challenges in the development of advanced drug delivery systems from natural-derived materials. It seeks to highlight significant advancements in nanoscale delivery systems, investigate their pharmacokinetics and pharmacodynamics in preclinical and clinical settings, and present novel approaches for enhancing drug delivery. The use of computational tools and physiologically-based pharmacokinetic models to predict therapeutic efficacy and safety is also a pivotal aspect of this research. Moreover, it underscores the development of sustainable nanomedicine formulations to reduce environmental footprints, steering towards the clinical translation of these innovative therapies.
To gather further insights in this dynamic field, we welcome contributions that are not limited to, but include the following themes:
• Biodegradable, biocompatible, and cytocompatible nanoformulations as drug carriers
• Biosafety, toxicity assessments, and environmental impacts of nanomedicines
• Green chemistry approaches in nanomedicine development
• Preclinical and clinical studies on pharmacokinetic and pharmacodynamic properties
• Translational pharmacology strategies for novel drug nanoformulations
• Use of PBPK models for dosage optimization, efficacy prediction, and safety assessment
• Regulatory challenges and strategies for clinical translation of nanotechnologies
We encourage submissions in the form of original research, reviews, mini-reviews, case reports, perspectives, and methodology articles, all aimed at advancing the field of natural-based nanomedicines.
Nanopharmacology integrates nanotechnology to revolutionize therapeutic and diagnostic applications, employing natural-based nanoformulations like alginate, chitosan, and hyaluronic acid among others. These formulations are gaining attention due to their potential to enhance drug delivery efficacy while reducing toxicity. The properties of these nanocarriers, such as biodegradability, biocompatibility, and cytocompatibility, position them as promising candidates in the development of advanced drug delivery systems and diagnostic tools. However, challenges such as optimizing pharmacological efficacy, ensuring biopharmaceutical stability, and addressing biosafety and environmental impacts are critical hurdles that impede their clinical translation.
This Research Topic aims to explore cutting-edge approaches that address the pharmacological, biopharmaceutical, and safety challenges in the development of advanced drug delivery systems from natural-derived materials. It seeks to highlight significant advancements in nanoscale delivery systems, investigate their pharmacokinetics and pharmacodynamics in preclinical and clinical settings, and present novel approaches for enhancing drug delivery. The use of computational tools and physiologically-based pharmacokinetic models to predict therapeutic efficacy and safety is also a pivotal aspect of this research. Moreover, it underscores the development of sustainable nanomedicine formulations to reduce environmental footprints, steering towards the clinical translation of these innovative therapies.
To gather further insights in this dynamic field, we welcome contributions that are not limited to, but include the following themes:
• Biodegradable, biocompatible, and cytocompatible nanoformulations as drug carriers
• Biosafety, toxicity assessments, and environmental impacts of nanomedicines
• Green chemistry approaches in nanomedicine development
• Preclinical and clinical studies on pharmacokinetic and pharmacodynamic properties
• Translational pharmacology strategies for novel drug nanoformulations
• Use of PBPK models for dosage optimization, efficacy prediction, and safety assessment
• Regulatory challenges and strategies for clinical translation of nanotechnologies
We encourage submissions in the form of original research, reviews, mini-reviews, case reports, perspectives, and methodology articles, all aimed at advancing the field of natural-based nanomedicines.