Advancements in Diversity and Drug Resistance Mechanisms in Mycobacterial Diseases

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144

authors

20

articles

Advancements in Diversity and Drug Resistance Mechanisms in Mycobacterial Diseases

80.9K

views

144

authors

20

articles

Editorial

02 March 2026

Editorial: Advancements in diversity and drug resistance mechanisms in mycobacterial diseases

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Editors

4

Samira Tarashi

Pasteur Institute of Iran (PII)

Svetlana Khaiboullina

University of Nevada, Reno

Manoj Baranwal

Thapar Institute of Engineering & Technology

Majid Marjani

National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences

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Advances in our understanding of diversity and drug resistance mechanisms in diseases caused by Mycobacterium spp. are essential for addressing the challenges posed by these pathogens. Members of the genus Mycobacterium have significant genetic diversity, resulting in virulence, pathogenicity, and antibiotic resistance variations.

Research has focused on uncovering the molecular mechanisms behind drug resistance, including mutations in target genes, efflux pumps, and biofilm formation. Additionally, studies on the genetic diversity of mycobacterial strains have shed light on the evolution and transmission dynamics of drug-resistant strains, assisting in the enhancement of diagnostic tools and treatment approaches.

Identifying new drug targets and developing novel antimicrobial agents are crucial research areas to address mechanisms of mycobacterial antimicrobial resistance. Understanding the diversity and drug resistance mechanisms in mycobacterial diseases is vital for developing effective interventions to combat these pathogens and enhance patient outcomes.

The purpose of this Research Topic is to compile the most recent advances in the field aimed at identifying the mechanisms of mycobacterial pathogenesis. Scientists are invited to submit their original research papers and review articles with the following potential, but not exhaustive, list of topics to include:

• Mechanisms of mycobacterial pathogenesis
• Mechanisms of mycobacterial drug resistance
• Advances in our understanding of genetic diversity of Mycobacterium species and strains
• Immune mechanisms and mycobacterial pathogenesis
• Gene, cell and gene-cell technologies-based diagnostics for Mycobacterium spp. caused diseases
• Genetic and environmental factors involved in pathogenesis and drug resistance of Mycobacterium spp.

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Editors

Samira Tarashi

Pasteur Institute of Iran (PII)

Svetlana Khaiboullina

University of Nevada, Reno

Manoj Baranwal

Thapar Institute of Engineering & Technology

Majid Marjani

National Research Institute of Tuberculosis and Lung Diseases, Shahid Beheshti University of Medical Sciences

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Published In

Frontiers in Microbiology

Antimicrobials, Resistance and Chemotherapy, Physiology and Metabolism of Microorganisms, Infectious Agents and Disease

Frontiers in Public Health

Infectious Diseases: Epidemiology and Prevention

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