The incidence of fungal diseases has increased in the last two decades due to the increase in vulnerable populations, although it is believed that other factors, such as climate change, may also be influencing. Among fungal diseases, candidiasis stands out as the most common, with the invasive form being the one that puts the lives of those who suffer from it at greatest risk. In the etiology of invasive candidiasis, only a few species (Candida albicans, C. tropicalis, C. glabrata, C. parapsilosis, and C. krusei) cause about 90% of cases. However, in recent years the emergence of new species of Candida has been recorded, some of them with high resistance to antifungals, such as C. auris. Likewise, the appearance of other yeasts, not belonging to the genus Candida, that cause invasive infection in humans has been reported. This appearance of new pathogenic fungi represents a challenge in the diagnosis and therapeutic management of invasive infections, so it is necessary to know their epidemiology, as well as new diagnostic and therapeutic tools for better management of patients.Therefore, this Research Topic aims to explore the current state of the epidemiology of invasive infections caused by rare or emerging yeasts, the attributes of virulence and susceptibility to antifungals, as well as advances in the diagnosis and treatment of yeast infections.To gather further insights in this area, we welcome original research, methods, reviews and mini reviews addressing, but not limited to, the following themes:- Epidemiological trends of new invasive yeasts species- Novel and improved diagnostic methodologies for early and accurate detection- Analysis of virulence factors and antifungal susceptibility- Current and novel therapeutic approaches to combat these infections
The incidence of fungal diseases has increased in the last two decades due to the increase in vulnerable populations, although it is believed that other factors, such as climate change, may also be influencing. Among fungal diseases, candidiasis stands out as the most common, with the invasive form being the one that puts the lives of those who suffer from it at greatest risk. In the etiology of invasive candidiasis, only a few species (Candida albicans, C. tropicalis, C. glabrata, C. parapsilosis, and C. krusei) cause about 90% of cases. However, in recent years the emergence of new species of Candida has been recorded, some of them with high resistance to antifungals, such as C. auris. Likewise, the appearance of other yeasts, not belonging to the genus Candida, that cause invasive infection in humans has been reported. This appearance of new pathogenic fungi represents a challenge in the diagnosis and therapeutic management of invasive infections, so it is necessary to know their epidemiology, as well as new diagnostic and therapeutic tools for better management of patients.Therefore, this Research Topic aims to explore the current state of the epidemiology of invasive infections caused by rare or emerging yeasts, the attributes of virulence and susceptibility to antifungals, as well as advances in the diagnosis and treatment of yeast infections.To gather further insights in this area, we welcome original research, methods, reviews and mini reviews addressing, but not limited to, the following themes:- Epidemiological trends of new invasive yeasts species- Novel and improved diagnostic methodologies for early and accurate detection- Analysis of virulence factors and antifungal susceptibility- Current and novel therapeutic approaches to combat these infections