Cancer neuroimmunology integrates the study of the nervous system's influence on tumor immunity, highlighting an intricate interaction that affects cancer progression and therapeutic outcomes. Recent discoveries posit the nervous system as a significant regulator, not just a bystander, in cancer dynamics. The central and peripheral nervous systems contribute to modulating the tumor microenvironment, influencing both neuroinflammation and immune responses. The relationship between neural activity and tumor immunity is further illustrated by the nervous system's potential to alter tumors' immune evasion tactics and influence the efficacy of immunotherapy. Additionally, phenomena like pain and stress-induced immune changes in cancer patients reveal gaps in our comprehensive understanding of the neuroimmune axis, suggesting a pivotal area for advanced research.
This Research Topic aims to delve into the complex interrelationships between neurobiology and immunology within the context of cancer. It seeks to elucidate the mechanisms through which the nervous system modulates tumor immunity and impacts responses to cancer therapies, thereby illuminating potential novel therapeutic pathways and improving current treatment modalities.
To thoroughly explore this emergent field, the Scope of this Research Topic is clearly defined yet broad in potential contributions. We are particularly interested in:
- Neuroimmune interactions in tumor progression and metastasis
- The nervous system's role in resistance to tumor immunotherapy
- Pain and stress-induced modulation of immune responses in cancer
- Effects of neuroinflammation and neurotrophic factors on the tumor microenvironment
- Influences of neurological disorders such as chronic pain and depression on cancer immunity
- Innovative therapeutic strategies that target the neuroimmune axis in oncology
We welcome contributions from diverse disciplines, including immunology, neurobiology, oncology, and clinical research, to provide a multifaceted view of the neuroimmune interplay in cancer. Contributions can include original research, reviews, and perspectives, and should be submitted through our peer-reviewed submission system. We encourage both basic and clinical studies that provide new insights into cancer neuroimmunology.
Cancer neuroimmunology integrates the study of the nervous system's influence on tumor immunity, highlighting an intricate interaction that affects cancer progression and therapeutic outcomes. Recent discoveries posit the nervous system as a significant regulator, not just a bystander, in cancer dynamics. The central and peripheral nervous systems contribute to modulating the tumor microenvironment, influencing both neuroinflammation and immune responses. The relationship between neural activity and tumor immunity is further illustrated by the nervous system's potential to alter tumors' immune evasion tactics and influence the efficacy of immunotherapy. Additionally, phenomena like pain and stress-induced immune changes in cancer patients reveal gaps in our comprehensive understanding of the neuroimmune axis, suggesting a pivotal area for advanced research.
This Research Topic aims to delve into the complex interrelationships between neurobiology and immunology within the context of cancer. It seeks to elucidate the mechanisms through which the nervous system modulates tumor immunity and impacts responses to cancer therapies, thereby illuminating potential novel therapeutic pathways and improving current treatment modalities.
To thoroughly explore this emergent field, the Scope of this Research Topic is clearly defined yet broad in potential contributions. We are particularly interested in:
- Neuroimmune interactions in tumor progression and metastasis
- The nervous system's role in resistance to tumor immunotherapy
- Pain and stress-induced modulation of immune responses in cancer
- Effects of neuroinflammation and neurotrophic factors on the tumor microenvironment
- Influences of neurological disorders such as chronic pain and depression on cancer immunity
- Innovative therapeutic strategies that target the neuroimmune axis in oncology
We welcome contributions from diverse disciplines, including immunology, neurobiology, oncology, and clinical research, to provide a multifaceted view of the neuroimmune interplay in cancer. Contributions can include original research, reviews, and perspectives, and should be submitted through our peer-reviewed submission system. We encourage both basic and clinical studies that provide new insights into cancer neuroimmunology.