Research Topic

Innovative Therapeutic and Immunomodulatory Strategies for Protozoan Infections

About this Research Topic

Human protozoan infections are an important target for development of new vaccines and drugs. No completely efficacious vaccines for human protozoan infections are available and in the case of malaria resistance to the most efficacious antimalarials has become a global challenge. In ocular toxoplasmosis complete eradication of the body is not possible, exposing patients to new reactivations.

The need of treatment or vaccines for Cryptosporidium and of less toxic drugs for Leishmania are urgent tasks for protozoologists research community. New research strategies have appeared that enlarged the possibilities for treatment and vaccine development. Reverse vaccinology, bioinformatic search of second use drug candidates and ex vivo analysis have afforded new fields for development. This Research Topic will look to examine these new possibilities, will bring together specialists and experiences that will feed the next wave of drugs and vaccines for this group of infections that have large consequences for human beings.

This Research Topic welcomes original contributions in the field of immunoinformatics, second use of drugs analysis and the in vivo and in vitro evaluation of new compounds against protozoa. Original contributions about second use compounds for protozoan diseases, application of immunoinformatics to identify new vaccine candidates and of chimioinformatics for the development of new drugs against theses parasitic diseases are of particular interest to be included in this project. Invited reviews from experts in the field will analyze the current developments and the critical points that still to be surmounted into the quest for efficacious and non toxic compounds and vaccines to be used in animal and human for theses diseases.

This Research Topic will be a precious tool to identify what is lacking in this field. The Topic will bring together different approaches looking for solutions to the sanitary problems of protozoan diseases.


Keywords: Vaccines, chimioinformatics, reverse vaccines, immunomodulation


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

Human protozoan infections are an important target for development of new vaccines and drugs. No completely efficacious vaccines for human protozoan infections are available and in the case of malaria resistance to the most efficacious antimalarials has become a global challenge. In ocular toxoplasmosis complete eradication of the body is not possible, exposing patients to new reactivations.

The need of treatment or vaccines for Cryptosporidium and of less toxic drugs for Leishmania are urgent tasks for protozoologists research community. New research strategies have appeared that enlarged the possibilities for treatment and vaccine development. Reverse vaccinology, bioinformatic search of second use drug candidates and ex vivo analysis have afforded new fields for development. This Research Topic will look to examine these new possibilities, will bring together specialists and experiences that will feed the next wave of drugs and vaccines for this group of infections that have large consequences for human beings.

This Research Topic welcomes original contributions in the field of immunoinformatics, second use of drugs analysis and the in vivo and in vitro evaluation of new compounds against protozoa. Original contributions about second use compounds for protozoan diseases, application of immunoinformatics to identify new vaccine candidates and of chimioinformatics for the development of new drugs against theses parasitic diseases are of particular interest to be included in this project. Invited reviews from experts in the field will analyze the current developments and the critical points that still to be surmounted into the quest for efficacious and non toxic compounds and vaccines to be used in animal and human for theses diseases.

This Research Topic will be a precious tool to identify what is lacking in this field. The Topic will bring together different approaches looking for solutions to the sanitary problems of protozoan diseases.


Keywords: Vaccines, chimioinformatics, reverse vaccines, immunomodulation


Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.

About Frontiers Research Topics

With their unique mixes of varied contributions from Original Research to Review Articles, Research Topics unify the most influential researchers, the latest key findings and historical advances in a hot research area! Find out more on how to host your own Frontiers Research Topic or contribute to one as an author.

Topic Editors

Loading..

Submission Deadlines

22 December 2017 Abstract
31 May 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..

Topic Editors

Loading..

Submission Deadlines

22 December 2017 Abstract
31 May 2018 Manuscript

Participating Journals

Manuscripts can be submitted to this Research Topic via the following journals:

Loading..
Loading..

total views article views article downloads topic views

}
 
Top countries
Top referring sites
Loading..

Comments

Loading..

Add a comment

Add comment
Back to top