About this Research Topic
This Research Topic honors the memory of Prof. Antonius (Ton) G. Rolink, our colleague, mentor and friend in immunology. This article collection, authored by many of Ton’s friends and colleagues, will reflect the huge contribution to cellular and molecular immunology that work emanating directly from Ton’s own hands and laboratory have made to the understanding of lymphocyte development. Ton’s hard work, expertise, generosity, passion for science and infectious humor were legendary and for all of those lucky enough to have been his colleague, he ensured that science was fun.
In addition to invited Original Research and Review articles by close colleagues of Ton, we welcome the submission of articles encompassing Ton’s range of scientific interests which include:
1. Autoimmunity associated with Graft-versus-Host Disease.
2. Basic cellular and molecular aspects of B and T lymphocyte, including regulatory T cell, development and function.
3. The use of novel stromal cell-based culture systems for studying lymphocyte development.
4. The role of soluble molecules such as IL-5, IL-7, Flt3 ligand, BAFF and chemokines in lymphocyte survival, proliferation and migration.
5. The role of transcription factors, in particular Pax-5 and OBF-1, in controlling hematopoietic cell lineage outcome.
This Research Topic will be introduced by three of Ton’s colleagues, Prof. Rhodri Ceredig, Prof. Hermann Eibel and Prof. Thomas Winkler. This will include brief extracts of personal tributes made to Ton by authors of scientific articles. Please submit an abstract prior to full manuscript submission to express your interest.
Keywords: Antonius G. Rolink, Autoimmunity, Lymphocyte development, Interleukins, Transcription factors
Important Note: All contributions to this Research Topic must be within the scope of the section and journal to which they are submitted, as defined in their mission statements. Frontiers reserves the right to guide an out-of-scope manuscript to a more suitable section or journal at any stage of peer review.