Integrating Multi-Omics to Explore Circulating and Tissue Immune Cell Profiles in Tumor Diagnosis and Therapy

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ORIGINAL RESEARCH

Published on 27 Jul 2026

CT-derived topological intratumoral heterogeneity predicts major pathological response to neoadjuvant immunochemotherapy in resectable non-small-cell lung cancer: a two-center study

Yongjie Zhou
Tingyu Hong
Hongliang Qi
Jinhong Zhao
Zhengyang Wu
Jingjing Du
Lan Liu
Fei Zou

doi 10.3389/fimmu.2026.1898208

228 views

ORIGINAL RESEARCH

Published on 17 Jul 2026

Association of intratumoral CD68+CD163+ M2-like macrophages with survival in metastatic colorectal cancer treated with chemotherapy plus bevacizumab

Xiaobin Xin
Huixian Qiu
Yan Zang
Lei Zhou
Tao Qin
Qingnuan Kong

doi 10.3389/fimmu.2026.1845691

742 views

REVIEW

Published on 29 May 2026

Recent advances in characterizing the immune microenvironment and biomarkers of endometrial carcinoma

Jianhong Ma
Guang Yao
Wei Wang

doi 10.3389/fimmu.2026.1779211

1,009 views

HYPOTHESIS AND THEORY

Published on 29 May 2026

A context-aware interpretive framework for lymphocyte immunophenotyping by flow cytometry

Carlos Agustin Villegas-Valverde
Yendry Ventura-Carmenate

doi 10.3389/fimmu.2026.1788361

1,422 views

ORIGINAL RESEARCH

Published on 12 May 2026

Multi-omics investigation of perineural invasion in head and neck squamous cell carcinoma: neuroimmune mechanisms and clinical implications

Muling Deng
Yuhao Lin
Chenyu Fang
Jiaqi Cai
Chuanben Chen
Jianming Ding

doi 10.3389/fimmu.2026.1792836

1,585 views

ORIGINAL RESEARCH

Published on 11 May 2026

Interpretable survival modeling integrating nutritional-inflammatory biomarkers in elderly patients with locally advanced esophageal squamous cell carcinoma treated with definitive radiotherapy

Jie Zou
Wenjing Fan
Xingzhuo Xia
Mengyue Zhang
Tingting Han
Qibing Wu

doi 10.3389/fimmu.2026.1836567

1,051 views

ORIGINAL RESEARCH

Published on 08 May 2026

Filaggrin as a potential biomarker in gastric cancer: insights from multi-omics analysis and experimental validation

Nan Xia
Tianru Ben
Xin Guan
Linlin Gao
Yuan Yuan

doi 10.3389/fimmu.2026.1742982

913 views

ORIGINAL RESEARCH

Published on 01 May 2026

Multi-omics integration of molecular genetics, cytogenetics and immunophenotyping: a novel prognostic model for immune landscape characterization and outcome prediction in Chinese patients with acute myeloid leukemia

Fengli Li
Yangyang Ding
Shanglong Feng
Yingzhao Jin
Beibei Xie
Qing Zhang
Xunyi Jiao
Jinli Zhu
Wanqiu Zhang
4 more
Zhimin Zhai

doi 10.3389/fimmu.2026.1812970

1,062 views

REVIEW

Published on 22 Apr 2026

Inflammation in hepatocellular carcinoma progression: a “Single Wick, dual interwoven strands” regulatory framework

Chao Wu
Jing Dong
Shangru Sui
Xiuyan Tan
Na Zhu

doi 10.3389/fimmu.2026.1822039

1,405 views

REVIEW

Published on 26 Feb 2026

The role of MiRNA-mediated tumor microenvironment in bone metastasis from a multi-omics perspective: cross-cancer mechanisms and clinical translation

Zhuo Gu
Shu-fen Zhu
Peng-fei Li

doi 10.3389/fonc.2026.1775016

1,389 views

SYSTEMATIC REVIEW

Published on 24 Feb 2026

Evolving epidemiology and improving safety of rechallenge in immune checkpoint inhibitor-associated acute kidney injury: an updated meta-analysis

Danyang Zhang
Xia Gu
Danyang Li
Yue Yang
Wenge Li

doi 10.3389/fimmu.2026.1777744

1,210 views
1 citation

ORIGINAL RESEARCH

Accepted on 06 Aug 2026

Integrated multi-omics analysis of metabolomics and proteomics uncovers dysregulated amino acid metabolism in HCC metastasis

Jing Wu
Jin Wang
Zhen Yu
Rui Yang

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Cancer Immunity and Immunotherapy

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Frontiers in Oncology
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Articles

CT-derived topological intratumoral heterogeneity predicts major pathological response to neoadjuvant immunochemotherapy in resectable non-small-cell lung cancer: a two-center study

Association of intratumoral CD68+CD163+ M2-like macrophages with survival in metastatic colorectal cancer treated with chemotherapy plus bevacizumab

Recent advances in characterizing the immune microenvironment and biomarkers of endometrial carcinoma

A context-aware interpretive framework for lymphocyte immunophenotyping by flow cytometry

Multi-omics investigation of perineural invasion in head and neck squamous cell carcinoma: neuroimmune mechanisms and clinical implications

Interpretable survival modeling integrating nutritional-inflammatory biomarkers in elderly patients with locally advanced esophageal squamous cell carcinoma treated with definitive radiotherapy

Filaggrin as a potential biomarker in gastric cancer: insights from multi-omics analysis and experimental validation

Multi-omics integration of molecular genetics, cytogenetics and immunophenotyping: a novel prognostic model for immune landscape characterization and outcome prediction in Chinese patients with acute myeloid leukemia

Inflammation in hepatocellular carcinoma progression: a “Single Wick, dual interwoven strands” regulatory framework

The role of MiRNA-mediated tumor microenvironment in bone metastasis from a multi-omics perspective: cross-cancer mechanisms and clinical translation

Evolving epidemiology and improving safety of rechallenge in immune checkpoint inhibitor-associated acute kidney injury: an updated meta-analysis

Integrated multi-omics analysis of metabolomics and proteomics uncovers dysregulated amino acid metabolism in HCC metastasis

Frontiers in Immunology

Cancer Immunity and Immunotherapy

Other participating journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy