Advances in Immunological Diagnostics for Infectious Diseases and Autoimmune Disorders: Novel Biomarkers, Serology, and Technological Developments

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ORIGINAL RESEARCH

Published on 30 Jul 2026

Development and validation of an interpretable machine learning model for the early diagnosis of invasive pulmonary aspergillosis in patients with severe fever with thrombocytopenia syndrome: a retrospective cohort study

Shuwen Ding
Ruize Ma
Wan Peng
Yanli Xu
Ling Lin
Zhihai Chen

doi 10.3389/fcimb.2026.1857200

546 views

ORIGINAL RESEARCH

Published on 09 Jul 2026

Early diagnostic value of serum S100 calcium-binding protein A12, serum amyloid A protein, and neutrophil-to-lymphocyte ratio in patients with acute empyema

Xiao-Lian Zhou
Dong-Qiong Li
Duo Li

doi 10.3389/fcimb.2026.1740584

486 views

ORIGINAL RESEARCH

Published on 11 Jun 2026

Common and rare variants in complement genes as biomarkers of COVID-19 infection and severity. A lesson to learn for emerging pathogens

María Eugenia De La Morena-Barrio
Ana Van Den Rym
Olga Escorial Sanz
Fernando Corvillo
Rosario García-Sánchez
Laura González-Sánchez
Adrián Muñoz-Barrera
Rafaela González-Montelongo
José Miguel Lorenzo-Salazar
11 more
Alberto López-Lera

doi 10.3389/fimmu.2026.1829115

1,362 views

ORIGINAL RESEARCH

Published on 04 Jun 2026

Immune imbalance markers: key factors in early recognition of multidrug-resistant bacterial infections in non-immunocompromised VAP patients

Mingying Tang
Qiyong Meng
Zhimin Huang
Yongjun Qing
Weijian Lei

doi 10.3389/fimmu.2026.1799042

1,356 views

ORIGINAL RESEARCH

Published on 29 May 2026

Single and combined use of the platelet–lymphocyte ratio and neutrophil–lymphocyte ratio in hemorrhagic fever with renal syndrome

Ting Wang
Kai Qi
Yaoni Li
Qiujian Zhao
Yazhou Yao
Lilan Zheng
Xingxing Zheng
Haodong Shi

doi 10.3389/fcimb.2026.1744838

1,631 views

ORIGINAL RESEARCH

Published on 22 May 2026

Impact of hepatitis B virus surface antigen mutations in the major hydrophilic region on antigen detectability

Chengshan He
Xuemei Gu
Yang Liu
Haitao Shen
Zhouhong Xiang
Zheng Xu

doi 10.3389/fcimb.2026.1831437

1,266 views
1 citation

METHODS

Published on 18 May 2026

Performance evaluation and application of a multiplex PCR capillary electrophoresis method for detecting nucleic acids of seven sexually transmitted pathogens

Yanping Dai
Kang Wang
Yong Wu
Wei Liang

doi 10.3389/fcimb.2026.1816857

1,129 views
1 citation

REVIEW

Published on 01 Apr 2026

Technological innovations and breakthrough pathways in syphilis diagnosis: addressing global resurgence and the journey toward elimination

Juan Hu
Chunyan Tan
Qin Li
Yanting Liu
Guangjun Xiao

doi 10.3389/fcimb.2026.1781460

2,343 views

SYSTEMATIC REVIEW

Published on 30 Mar 2026

An integrated immunopathological model of syphilis serofast: a systematic review and meta-analysis

Yong-Xin Zeng
Lin Yang
Yuan-Yuan He
Zi-Liang Deng
Wu-Jian Ke
Hai-Ying Wang

doi 10.3389/fimmu.2026.1758075

1,672 views
2 citations

ORIGINAL RESEARCH

Published on 04 Mar 2026

Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn’s disease

Konstantina Zafeiropoulou
Ishtu L. Hageman
Tianqi Mu
Mark Davids
Andrew Y. F. Li Yim
Vincent W. Joustra
Theodorus B. M. Hakvoort
Jack Satsangi
Konstantinos Chronas
4 more
Wouter J. de Jonge

doi 10.3389/fcimb.2026.1741002

1,633 views

SYSTEMATIC REVIEW

Published on 26 Feb 2026

Identifying the thresholds of C-reactive protein, procalcitonin, and interleukin-6 among children ≤36 months’ old with fever without source at risk of serious bacterial infections: a systematic review and meta-analysis

Natalia Sutiman
Jiaying Lin
Rehena Sultana
Sarah Hui Wen Yao
Sharon Si Min Goh
Suzanne-Kae Rocknathan
Sashikumar Ganapathy
Shu-Ling Chong

doi 10.3389/fped.2026.1697210

2,555 views

BRIEF RESEARCH REPORT

Published on 23 Feb 2026

The unsung hero: ntnh gene as complementary botulism marker

Sylvia Valdezate
Mónica Valiente
Sergio Díaz-Ramón
Gema Carrasco
María J. Medina-Pascual
Javier Pardos
María Isabel Hurtado
Noelia Garrido
Pilar Villalón
Antonio J. Martín-Galiano

doi 10.3389/fcimb.2026.1758429

1,175 views

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Clinical and Diagnostic Microbiology and Immunology

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Articles

Development and validation of an interpretable machine learning model for the early diagnosis of invasive pulmonary aspergillosis in patients with severe fever with thrombocytopenia syndrome: a retrospective cohort study

Early diagnostic value of serum S100 calcium-binding protein A12, serum amyloid A protein, and neutrophil-to-lymphocyte ratio in patients with acute empyema

Common and rare variants in complement genes as biomarkers of COVID-19 infection and severity. A lesson to learn for emerging pathogens

Immune imbalance markers: key factors in early recognition of multidrug-resistant bacterial infections in non-immunocompromised VAP patients

Single and combined use of the platelet–lymphocyte ratio and neutrophil–lymphocyte ratio in hemorrhagic fever with renal syndrome

Impact of hepatitis B virus surface antigen mutations in the major hydrophilic region on antigen detectability

Performance evaluation and application of a multiplex PCR capillary electrophoresis method for detecting nucleic acids of seven sexually transmitted pathogens

Technological innovations and breakthrough pathways in syphilis diagnosis: addressing global resurgence and the journey toward elimination

An integrated immunopathological model of syphilis serofast: a systematic review and meta-analysis

Colonic biopsy-associated microbial signatures are predictive of response to anti-TNFα biological therapy in Crohn’s disease

Identifying the thresholds of C-reactive protein, procalcitonin, and interleukin-6 among children ≤36 months’ old with fever without source at risk of serious bacterial infections: a systematic review and meta-analysis

The unsung hero: ntnh gene as complementary botulism marker

Frontiers in Cellular and Infection Microbiology

Clinical and Diagnostic Microbiology and Immunology

Other participating journals

Frontiers in Immunology

Microbial Immunology