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Memory Reconsolidation: Current Research and Future Directions

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The question whether items in long-term memory consolidate only just once per item or, alternatively, undergo recurrent consolidation-like processes upon reactivation, is key to understanding memory storage, stability and veracity, as well as to potential amelioration of post-traumatic disorders. Interest in ...

The question whether items in long-term memory consolidate only just once per item or, alternatively, undergo recurrent consolidation-like processes upon reactivation, is key to understanding memory storage, stability and veracity, as well as to potential amelioration of post-traumatic disorders. Interest in this question has been revitalized in recent years, as attested by a surge of cutting edge publications and lively debates. This revitalization can be traced back to the year 2000, particularly, to the publication of the signal experimental paper on reconsolidation of fear memory by Nader, Schafe and LeDoux (Nature 406, 722), and of the comprehensive review of earlier data by Sara (Learning & Memory 7, 73).


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