T-Cell redirecting therapies in oncology

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Articles

GENERAL COMMENTARY

Published on 09 Jul 2026

Commentary: Case Report: CAR-T cell therapy bridging to allogeneic hematopoietic stem cell transplantation triggers Purtscher-like retinopathy: clinical features and complement-mediated microvascular injury mechanisms

Igor Resnick
Mladena Radeva

doi 10.3389/fimmu.2026.1847573

238 views

ORIGINAL RESEARCH

Published on 16 Jun 2026

Predicting CAR-T outcomes in R/R DLBCL: a multicenter real-world study of a 5-index model

Bin Xue
Huina Lu
Yifan Liu
Ying Lu
Wenjun Zhang
Bing Xiu
Xiu Luo
Li Wang
Wenbin Qian
1 more
Ping Li

doi 10.3389/fimmu.2026.1863194

827 views

REVIEW

Published on 03 Jun 2026

T-cell engagers in cancer immunotherapy: mechanisms, challenges, and future perspectives

Kaaviyaa Muthughavi
Manoj Khokhar
Hem Chandra Chandra Jha
Rajan Kumar Kumar Pandey

doi 10.3389/fimmu.2026.1755512

1,802 views

ORIGINAL RESEARCH

Published on 03 Jun 2026

Impact of TP53 mutations on survival outcomes in the CAR-T era of large B-cell lymphoma

Rui Liu
Zhonghua Fu
Fan Yang
Miaomiao Cao
Lixia Ma
Yuelu Guo
Biping Deng
Qinlong Zheng
Chen Chen
4 more
Kai Hu

doi 10.3389/fimmu.2026.1823432

1,141 views

REVIEW

Published on 01 Jun 2026

From monoclonals to bispecific T cell engagers: the evolving antibody-based therapy landscape in acute myeloid leukemia

Milad Rasouli
Marie Dalem
Marc H.G.P. Raaijmakers
Peter D. Katsikis
Stefan J. Erkeland

doi 10.3389/fimmu.2026.1803185

2,018 views

ORIGINAL RESEARCH

Published on 17 Apr 2026

Discovery of co-stimulatory anti-CD28 VHHs for developing cancer immune therapeutic anti-tumor/CD3/CD28 trispecific T cell engager

Hui Wang
Rui Zhao
Mengmeng Liu
Tianzhi Jiang
Di Sun
Lida Chi
Yonglin Huang
Zhenghui Lu
Yueli Yun
Xiangbin Wang

doi 10.3389/fimmu.2026.1812063

2,126 views
1 citation

CASE REPORT

Published on 27 Mar 2026

Case Report: Durable remission of intraocular mantle cell lymphoma after CD19 CAR-T therapy

Álvaro Bienert-García
Carolina Arruabarrena
Mónica Asencio-Duran
Marta Morado Arias
Tycho Baumann
Antonia Rodriguez Izquierdo
José María Sánchez-Pina
Nieves López-Muñoz
Daniel Gil-Alós
3 more
Ana Jiménez-Ubieto

doi 10.3389/fimmu.2026.1786040

1,040 views

ORIGINAL RESEARCH

Published on 06 Mar 2026

Real-world safety profile of T-cell engagers: evidence from multi-database analysis with CAR-T comparisons

Jinman Zhong
Chang Chen
Yunman Xu
Yueping He
Jingwen Luo
Changxiu Zhang
Jiewen Tan
Dan Xiong

doi 10.3389/fimmu.2026.1740144

2,387 views

MINI REVIEW

Accepted on 29 Jun 2026

Integrating T Cell Signaling and Metabolism to Enhance T Cell Engager Responses in Solid Tumors

Michael Scaglione
Minal Engavale
Matthew G Chun
Deepali V Sawant
Daniel R Lu
Edward LaGory

240 views

ORIGINAL RESEARCH

Accepted on 30 Jun 2026

Clinical determinants of survival outcomes and acute toxicity after adoptive cellular therapy for solid tumors

Jeong Uk Lim
Derrick Tao
Paul Nevins Selvadurai
Ecaterina Dumbrava
Aung Naing
Stephane Champiat
Lei Kang
Hung Le
Apostolia Maria Tsimberidou
7 more
David S Hong

227 views

SYSTEMATIC REVIEW

Accepted on 01 Jul 2026

Efficacy, Safety, and Characteristics of Adoptive Tumor-Infiltrating Lymphocyte (TIL) Therapy in Solid Tumours: A Systematic Review and Meta-Analysis

Haripriya Parapparambil Surendran
Gopal Gopisetty
Senthil J Rajappa
Subramanyeshwar T Rao
Unnikrishnan Mazhuvanchery Kesavan

191 views

REVIEW

Accepted on 06 Jul 2026

Beyond exhaustion: T cell fitness for next generation of immunotherapy for hematological cancer

Xiaoshuang Kong
Yuanhui Su
Hanxue Zheng
Zuxi Feng
Jianxia Huang
Liansheng Zhang
Lijuan Li

148 views

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Frontiers in Immunology

Cancer Immunity and Immunotherapy
T Cell Biology

Other participating journals

Frontiers in Oncology
- Cancer Immunity and Immunotherapy
- 3.4 impact factor
- 6.6 citescore

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Articles

Commentary: Case Report: CAR-T cell therapy bridging to allogeneic hematopoietic stem cell transplantation triggers Purtscher-like retinopathy: clinical features and complement-mediated microvascular injury mechanisms

Predicting CAR-T outcomes in R/R DLBCL: a multicenter real-world study of a 5-index model

T-cell engagers in cancer immunotherapy: mechanisms, challenges, and future perspectives

Impact of TP53 mutations on survival outcomes in the CAR-T era of large B-cell lymphoma

From monoclonals to bispecific T cell engagers: the evolving antibody-based therapy landscape in acute myeloid leukemia

Discovery of co-stimulatory anti-CD28 VHHs for developing cancer immune therapeutic anti-tumor/CD3/CD28 trispecific T cell engager

Case Report: Durable remission of intraocular mantle cell lymphoma after CD19 CAR-T therapy

Real-world safety profile of T-cell engagers: evidence from multi-database analysis with CAR-T comparisons

Integrating T Cell Signaling and Metabolism to Enhance T Cell Engager Responses in Solid Tumors

Clinical determinants of survival outcomes and acute toxicity after adoptive cellular therapy for solid tumors

Efficacy, Safety, and Characteristics of Adoptive Tumor-Infiltrating Lymphocyte (TIL) Therapy in Solid Tumours: A Systematic Review and Meta-Analysis

Beyond exhaustion: T cell fitness for next generation of immunotherapy for hematological cancer

Frontiers in Immunology

Cancer Immunity and Immunotherapy

T Cell Biology

Other participating journals

Frontiers in Oncology

Cancer Immunity and Immunotherapy